DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14855 and CG14857

DIOPT Version :9

Sequence 1:	NP_650390.2	Gene:	CG14855 / 41789	FlyBaseID:	FBgn0038260	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_650392.1	Gene:	CG14857 / 41791	FlyBaseID:	FBgn0038262	Length:	560	Species:	Drosophila melanogaster

Alignment Length:	527	Identity:	282/527 - (53%)
Similarity:	389/527 - (73%)	Gaps:	4/527 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFEEILAKCGNSSRYQFVLLALYGYLMVVVSMHYFSQNVISFVPDHWCYHEQLENRSFAEIEKI 65
            |||::||.|||::.|||::::.|.||:....::||:|||:|.|||.||||||.||||||.||..|
  Fly     1 MDFDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALENRSFEEIAAI 65

  Fly    66 YSQFEK-PSCTRLEKIDEDGQNHTLSRERCNRWIYKYDFGYKSMNTELNWVCDEAYKARVGQSLF 129
            |:.|.| .|||||:||  :|...|:|.|.|.||||.||||::|||.||||||::|||||:|||||
  Fly    66 YAPFGKEASCTRLDKI--EGDRVTVSNETCQRWIYNYDFGFRSMNAELNWVCNDAYKARIGQSLF 128

  Fly   130 FVGSVCGTLAFGLLGDRIGRIRALILANWCGFLGDFSTIFAGSLTSFSISRFISGLAADANSYLM 194
            |:||:.||..||:|||||||:||:||||.|||:|||.|.:|.:|..|:|.|.||||||.||.|||
  Fly   129 FLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYASNLVQFAIFRCISGLAATANYYLM 193

  Fly   195 YILILEYVSPSLRNVGLNTVLGSFYCLGLIGACWLAVWVGHWRIFLACSSVPLLLVTLFYFLVQE 259
            :||:|||::|.|||:.::..||..:|||.:.|.||:|..|:|||:|.||::..|:|.||||:|||
  Fly   194 FILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSVLAGNWRIYLTCSALLQLVVALFYFVVQE 258

  Fly   260 SAQWLVTRNDVDGAIRRLERVAKINRRQVADKDFKDFRIYCEQHYRKDKNQEEHAKLLDMLKTPR 324
            |||||:||.:|:|||.||:.:|..|..:|...||:.||..|....:.....|:.|.:.|:|:||.
  Fly   259 SAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCIVKRKLSNQPEQTAGIFDLLRTPN 323

  Fly   325 MRSTAFKLLLIFIIIVPCYNTIARNVEGLGISPFIMFSLNALTLPPSGYLQGLLQDRMGRKATAV 389
            :|..:..::..|::....:|||:|||||:|:|||::|||.|:.:||||::|||||.|:||||||.
  Fly   324 LRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAF 388

  Fly   390 GWMAITGIFAVAAGLVIS-QGSNRNVLLLVGLTMAARFGVSIADGASSQFSTELIPTSVRGRGVA 453
            ..|..||:.:.|.|:.:| :|:.:||.||:...:..|.|:|:....:|||::||:||.||.||:|
  Fly   389 LAMLCTGLLSCALGVALSTEGAQKNVTLLLAFALPMRLGISMCYTVTSQFASELLPTCVRSRGIA 453

  Fly   454 VVHVAGFAASFLSPYILHLGTYYKPAPSIILGLLFLSGAYVCLLLPETRNKKLPMSLAEGEEFGR 518
            .||:|...|||:|||::||||....|||:||.||.|:.:...|:||||.|::||::||:||.||:
  Fly   454 AVHLAAAGASFVSPYLIHLGTKLAAAPSLILALLLLTASGCTLMLPETNNRQLPITLADGEAFGK 518

  Fly   519 GEGIFDF 525
            ||.:..|
  Fly   519 GESMLSF 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	264/497 (53%)
CG14855	NP_650390.2	MFS	127..499	CDD:119392	189/372 (51%)
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	266/499 (53%)
CG14857	NP_650392.1	MFS	126..470	CDD:119392	176/343 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471360
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BGEV
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	1	1.000	-	-		FOG0006714
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	8	7.860