Protein Alignment CG14855 and SLC22A10

DIOPT Version :9

• Sequence 1: NP_650390.2
• Gene: CG14855 / 41789
• FlyBaseID: FBgn0038260
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001034841.3
• Gene: SLC22A10 / 387775
• HGNCID: 18057
• Length: 541
• Species: Homo sapiens
• Alignment Length: 552
• Identity: 134/552 - (24%)
• Similarity: 239/552 - (43%)
• Gaps: 59/552 - (10%)

  Fly     1 MDFEEILAKCGNSSRYQFV-LLALYGYLMVVVSMHYFSQNVISFVPDHWCYHEQLENRSFAEIE- 63
            |.|||:|::.|...|:|.: |:.:...||:::. |...:|..:.:|.|.|:...|:|.:.:..|
Human     1 MAFEELLSQVGGLGRFQMLHLVFILPSLMLLIP-HILLENFAAAIPGHRCWVHMLDNNTGSGNET 64

  Fly    64 -------------KIYSQFEKPSCTRL-----EKIDEDGQNHTLSR---ERC-NRWIYKYDFGYK 106
                         .:.|......|.|.     :.:..:|..|:.|.   |.| :.|:|...:...
Human    65 GILSEDALLRISIPLDSNLRPEKCRRFVHPQWQLLHLNGTIHSTSEADTEPCVDGWVYDQSYFPS 129

  Fly   107 SMNTELNWVCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGRIRALILANWCGF---LGDFSTI 168
            ::.|:.:.|||......|.|.|...|.:.|.:..|.:.||.||   ..:..||..   :.|....
Human   130 TIVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGHVSDRFGR---RFILRWCLLQLAITDTCAA 191

  Fly   169 FAGSLTSFSISRFISGLAADANSYLMYIL------ILEYVSPSLRNVGLNTVLGS-FYCLGLIGA 226
            ||.:...:.:.||::|.::      |.|:      |.|::.|:.:  .|..:|.| ...:|.|..
Human   192 FAPTFPVYCVLRFLAGFSS------MIIISNNSLPITEWIRPNSK--ALVVILSSGALSIGQIIL 248

  Fly   227 CWLAVWVGHWRIFLACSSVPLLLVTLFYFLVQESAQWLVTRNDVDGAIRRLERVAKINRRQVADK 291
            ..||.....|:.....:|||..:..|....:.|||:||:..|.:|..::.|.:||:.|..:.|::
Human   249 GGLAYVFRDWQTLHVVASVPFFVFFLLSRWLVESARWLIITNKLDEGLKALRKVARTNGIKNAEE 313

  Fly   292 DFKDFRIYCEQHYRKDKNQEEHAKLLDMLKTPRMRSTAFKLLLI-FIIIVPCYNTIARNVEGLGI 355
            ......:........|..|.: ..:.|:.:.|.||.....|:.: |...:|.|.|:. |::.:|.
Human   314 TLNIEVVRSTMQEELDAAQTK-TTVCDLFRNPSMRKRICILVFLRFANTIPFYGTMV-NLQHVGS 376

  Fly   356 SPFIMFSLNALTLPPSGYLQGLLQDRMGRKATAVGWMAITGIFAVAAGLVISQGSNRNVLLL--- 417
            :.|::..|..........|..|..:.|||:.:.:.:|.:.|:..:|...|..:.....|.|.
Human   377 NIFLLQVLYGAVALIVRCLALLTLNHMGRRISQILFMFLVGLSILANTFVPKEMQTLRVALACLG 441

  Fly   418 VGLTMAARFGVSIADGASSQFSTELIPTSVRGRGVAVVHVAGFAASFLSPYILHLGTYYKPAPSI 482
            :|.:.|....|::       ...|||||.:|.|...:...|....:.|:|.::.|..::...|.|
Human   442 IGCSAATFSSVAV-------HFIELIPTVLRARASGIDLTASRIGAALAPLLMTLTVFFTTLPWI 499

  Fly   483 ILGLLFLSGAYVCLLLPETRNKKLPMSLAEGE 514
            |.|:..:.|..:..|||||:|..||.::.:.|
Human   500 IYGIFPIIGGLIVFLLPETKNLPLPDTIKDVE 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	126/533 (24%)
		MFS	127..499	CDD:119392	91/385 (24%)
SLC22A10	NP_001034841.3	2A0119	11..526	CDD:273328	128/535 (24%)
		MFS	143..516	CDD:119392	93/392 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153693
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.940