Protein Alignment CG14855 and Slc22a14

DIOPT Version :9

• Sequence 1: NP_650390.2
• Gene: CG14855 / 41789
• FlyBaseID: FBgn0038260
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001032838.1
• Gene: Slc22a14 / 382113
• MGIID: 2685974
• Length: 629
• Species: Mus musculus
• Alignment Length: 616
• Identity: 137/616 - (22%)
• Similarity: 238/616 - (38%)
• Gaps: 122/616 - (19%)

  Fly     3 FEEILAKCGNSSRYQFVLLALYGYLMVVVSMHYFSQNVISFVPDHWC-------------YHEQL 54
            |..::...|....:|:.|:.|.....::.:...||.:.:......:|             ..|||
Mouse    51 FASVMDAIGEFGTFQWRLVVLTFIPSILSTFFIFSHHFLLTAQRPYCNTSWILEVGPNLTEDEQL 115

  Fly    55 E-------NRSFAEIEKIYSQFEKPSCTR-------LEKIDEDGQNHTLSRERCN-RWIYKYDFG 104
            .       |.||.            :|..       |:.|...|.|:|   |.|. .|||.:..
Mouse   116 NLTLPRAPNGSFL------------TCLMYIPVPWDLDSIIHFGLNYT---ETCKFGWIYPFAH- 164

  Fly   105 YKSMNTELNWVCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGRIRALILANWCGFL-GDFSTI 168
            .:|:..|.:.||........|.::|..|.:.|:|.||.|.|::||. .:||.:..||| ..|.|.
Mouse   165 TRSLINEFDLVCGNEPNKENGLTVFLSGVLTGSLLFGFLSDKLGRY-PIILLSLLGFLIFGFGTA 228

  Fly   169 FAGSLTSFSISRFISGLAADANSYLMYILILEYVSPSLRNVGLNTVLGSFYCLGLIGACWLAVWV 233
            |..|...:...||....|:...:.....|::|::....|...: .:..||..:|:|....||..|
Mouse   229 FVSSFYQYLFFRFFVAQASVGYAICSVSLVMEWLVGEHRAQAV-ILQHSFLTIGVILLTGLAYKV 292

  Fly   234 GHWRIFLACSSVPLLLVTLFYFLVQESAQWLVTRNDVDGAIRRLERVAKINRRQVADKDFKDFRI 298
            .|||:......:|:..:....::::||.:||:.|..|:.|.:.|...|::|::.:......:.:|
Mouse   293 VHWRLLCLLGGMPMFPLICNIWVLRESPRWLMVRGKVEEAKKVLCYAAEVNKKTIPLNLLNELQI 357

  Fly   299 YCEQHYRKDKNQEEHAKLLDMLKTPRMRSTAFKLLL----IFIIIVPCYNTIARNVEGLGISPFI 359
                    ...:...|.:||......:    ||::|    ::..:.....|:...:...|:..:.
Mouse   358 --------SGKKVAKASILDFCTNQHL----FKVVLAIGCVWFTVSYISFTLNLKMNDFGLDVYF 410

  Fly   360 MFSLNALTLPPSGYLQGLLQDRMGRKATAVGWMAITGIFAVAAG----LVISQGSNRNVLLLVGL 420
            :..:.::...|:.....:|.:..|||     |.....:|.|.:.    |.:.|.....::|.:
Mouse   411 VQMVRSIVAVPARLCCIILLEYFGRK-----WALNLTLFLVTSMCLFLLFLPQEPKSTIILTL-- 468

  Fly   421 TMAARFGVSIADGASSQF---STELIPTSVRGRGVAVVHVAGFAASFLSPYILHLGTYYKP---- 478
             |.|.|.::   |..|.|   :.||:||.:|..|:.:|.:|..|.:..|..|........|
Mouse   469 -MLAEFSMA---GTLSIFFIYTAELLPTVLRSTGLGMVSLAWVAGAISSVAIFKQTKTQLPIFFC 529

  Fly   479 APSIILGLLFLSGAYVCLLLPET---------------------RNKKLPMSLAEGEEFGRGEGI 522
            ....:|.|.|.|      |:|||                     |||.:||.:||       |.:
Mouse   530 CLCCVLALCFSS------LVPETGSQSLRDSIEYNIRDSIEPKDRNKDVPMVIAE-------ESM 581

  Fly   523 FDFLRHMFRREGSKSEVEMGPTIVEEDTLIN 553
            .|.:........:.:.|...|   ||::|:|
Mouse   582 SDIVADSEVTNTTLNAVTFKP---EENSLLN 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	124/560 (22%)
		MFS	127..499	CDD:119392	89/387 (23%)
Slc22a14	NP_001032838.1	2A0119	59..553	CDD:273328	121/540 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844081
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.030