Protein Alignment CG14855 and Slc22a30

DIOPT Version :10

• Sequence 1: NP_650390.2
• Gene: CG14855 / 41789
• FlyBaseID: FBgn0038260
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_795976.1
• Gene: Slc22a30 / 319800
• MGIID: 2442750
• Length: 552
• Species: Mus musculus
• Alignment Length: 601
• Identity: 155/601 - (25%)
• Similarity: 256/601 - (42%)
• Gaps: 103/601 - (17%)

  Fly     1 MDFEEILAKCGNSSRYQFVLLALYGYLMVVVSMHYFSQNVISFVPDHWCYHEQLENRSFAEI-EK 64
            |.|:|:|.:.|:..|:|.:.::...:|:.:|..|...:|..:.:|:|.|:...|:|.:.::. .:
Mouse     1 MAFQELLNQVGSLGRFQILQISFVLFLVGLVVPHITMENFTAAIPNHRCWAPILDNDTASDNGSR 65

  Fly    65 IYSQ-------FEKPSCTRLEKIDEDGQ--------NHTLSRER------C-NRWIYKYDFGYKS 107
            |.||       ....|..||:|.....|        |.|.|.|.      | :.|:|.......:
Mouse    66 ILSQDDLLRISIPLDSNLRLDKCRRFAQPQWHLLHLNGTFSNETEPDTEPCVDGWVYDRSNFLST 130

  Fly   108 MNTELNWVCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGRIRALILANWCGFLGDFSTIFAGS 172
            :.||.:.||:......|.:..|.:|...|.:..|.|.||.||...|..|.....:.:....||.|
Mouse   131 IVTEWDLVCESQALNSVAKFSFMIGLFIGAIICGHLSDRFGRKFILTCALLQFAITETCVAFAPS 195

  Fly   173 LTSFSISRFISGLAADANSYLMYILILEYVSPSLRNVGLNTVLGSFYCLGLIG---ACWLAVWVG 234
            ...:.:.||::|::.:..|...::|:||:.||..  :|:..||.|  |...||   ...||....
Mouse   196 FFIYCLLRFLAGMSVEPISVNSHLLMLEWTSPKF--LGMVAVLTS--CAASIGYMILAGLAFLFR 256

  Fly   235 HWRIFLACSSVPLLLVTLFYFLV-----QESAQWLVTRNDVDGAIRRLERVAKINRRQVADKDFK 294
            .||......|||     :|:||:     .|||:||:..|.....::.|.:||.:|..:.:..
Mouse   257 IWRHLQLAMSVP-----IFFFLILTRWMSESARWLIVTNKPQKGLKELRKVAHMNGMKNSGN--- 313

  Fly   295 DFRIYCEQHYRKDKNQEEHAKL----LDMLKTPRMRS----TAFKLLLIFIIIVPCYNTIARNVE 351
              .:..|......||:.|.||.    .|:..||.:|.    .:|...|..|.|
Mouse   314 --TLTMEVVEASMKNELEAAKRKSSPRDLFHTPILRKRICVLSFMRYLFTISI------------ 364

  Fly   352 GLGISPFIM-FSLNALTLPPSGYLQGLL--------QDRMGRKATAVGWMAITGIFAVAAGLVIS 407
             .|:|..:. .|.|.:.|.......|:|        .:.|||:.|.:..|::.|||.:.|..|..
Mouse   365 -FGLSLHLQHLSTNIILLQFLSSALGILISVIGHFVLNHMGRRITQLVLMSLRGIFMLTAVFVPQ 428

  Fly   408 QGSNRNVLLLVGLTMAARFGVSIADGASSQFSTELIPTSVRGRGVAVVHVAGFAASFLSPYILHL 472
            :   ...|.::..|:||... |:....|:....||:||::|..|:.|:.:.|.:..||:|..:.|
Mouse   429 E---MQTLRIIMATLAAALS-SLCMCVSNLHINELLPTTLRATGMGVIAMFGNSGLFLAPLFMLL 489

  Fly   473 GTYYKPAPSIILGLLFLSGAYVCLLLPETRNKKLPMSLAE-GEEFGRGEGIFDFLRHMFRREGSK 536
            .||....|.|..|...:...:...|||||:|:.||.|:.: |.::               :|..:
Mouse   490 ATYSANLPWIFYGGFSILYGFSVFLLPETKNQPLPDSIHDVGNDW---------------KESRQ 539

  Fly   537 SEVEMGPTIVEEDTLI 552
            ::        |||::|
Mouse   540 AK--------EEDSII 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	142/543 (26%)
Slc22a30	NP_795976.1	MFS_OAT	109..516	CDD:340932	113/437 (26%)