Protein Alignment CG14855 and Slc22a12

DIOPT Version :9

• Sequence 1: NP_650390.2
• Gene: CG14855 / 41789
• FlyBaseID: FBgn0038260
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Alignment Length: 560
• Identity: 143/560 - (25%)
• Similarity: 245/560 - (43%)
• Gaps: 79/560 - (14%)

  Fly     1 MDFEEILAKCGNSSRYQ-FVLLALYGYLMVVVSMHYFSQNVISFVPDHWCYHEQLENRSFAEIEK 64
            |.|.|:|.:.|...|:| |..:||...::.|.:.:.. :|..:.||.|.|:...|:|.:
Mouse     1 MAFPELLDRVGGLGRFQLFQTVALVTPILWVTTQNML-ENFSAAVPHHRCWVPLLDNST------ 58

  Fly    65 IYSQFEKP----------------------SCTRLE----KIDEDGQNHT----LSRERC-NRWI 98
              ||...|                      .|.|..    ::.|.....|    .:.|.| :.|:
Mouse    59 --SQASIPGDLGPDVLLAVSIPPGPDQQPHQCLRFRQPQWQLTESNATATNWSDAATEPCEDGWV 121

  Fly    99 YKYDFGYKSMNTELNWVCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGRIRALILANWCGFLG 163
            |.:.....::.|..:.||:......:.||:|..|.:.|....|...||.||.|.|   .|...|.
Mouse   122 YDHSTFRSTIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVL---TWSYLLV 183

  Fly   164 DFSTIFAGSLTSFSISRFISGLAADANSYLMY---ILILEYV----SPSLRNVGLNTVLGSFYCL 221
            ..|...|..:.:|.:......|.|.|.:.:|.   .|::|:.    ||.:..:   ..||..:..
Mouse   184 SVSGTAAAFMPTFPLYCLFRFLLASAVAGVMMNTASLLMEWTSAQGSPLVMTL---NALGFSFGQ 245

  Fly   222 GLIGACWLAVWVGHWRIFLACSSVPLLLVTLFYFLVQESAQWLVTRNDVDGAIRRLERVAKINRR 286
            .|.|:  :|..|..||:.....|.|..|..::.:.:.|||:||:|...:|..::.|:|||.:|||
Mouse   246 VLTGS--VAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKLDQGLQELQRVAAVNRR 308

  Fly   287 QVADKD---FKDFRIYCEQHYRKDKNQEEHAKLLDMLKTPRMRSTAFKLLLIFIIIVPCYNTIAR 348
            : |:.|   .:..|...|:...:||   ..|.|..:|.||.:|......:|.:......:..:|.
Mouse   309 K-AEGDTLTMEVLRSAMEEEPSRDK---AGASLGTLLHTPGLRHRTIISMLCWFAFGFTFYGLAL 369

  Fly   349 NVEGLGISPFIMFSLNALTLPP--SGYLQGLLQDRMGRKATAVGWMAITGIFAVAAGLVISQGSN 411
            :::.||.:.|::.:|..:...|  :|.|  ||..|:||:...|.::.:.|: .:.:.:::..|..
Mouse   370 DLQALGSNIFLLQALIGIVDFPVKTGSL--LLISRLGRRLCQVSFLVLPGL-CILSNILVPHGMG 431

  Fly   412 --RNVLLLVGL-TMAARFG-VSIADGASSQFSTELIPTSVRGRGVAVVHVAGFAASFLSPYILHL 472
              |:.|.::|| .:...|. ::|       ||:||.||.:|...|.:..||....:.|.|.:..|
Mouse   432 VLRSALAVLGLGCLGGAFTCITI-------FSSELFPTVIRMTAVGLCQVAARGGAMLGPLVRLL 489

  Fly   473 GTYYKPAPSIILGLLFLSGAYVCLLLPETRNKKLPMSLAE 512
            |.|....|.::.|::.:......||||||:|..||.::.:
Mouse   490 GVYGSWMPLLVYGVVPVLSGLAALLLPETKNLPLPDTIQD 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	137/543 (25%)
		MFS	127..499	CDD:119392	103/387 (27%)
Slc22a12	NP_033229.3	2A0119	11..526	CDD:273328	139/545 (26%)
		MFS	147..516	CDD:119392	104/390 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843321
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950