Protein Alignment CG14855 and Slc22a2

DIOPT Version :9

• Sequence 1: NP_650390.2
• Gene: CG14855 / 41789
• FlyBaseID: FBgn0038260
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_038695.1
• Gene: Slc22a2 / 20518
• MGIID: 1335072
• Length: 553
• Species: Mus musculus
• Alignment Length: 575
• Identity: 146/575 - (25%)
• Similarity: 238/575 - (41%)
• Gaps: 105/575 - (18%)

  Fly     4 EEILAKCGNSSRYQ---FVLLALYGYLMVVVSMHYFSQNVISFVPDHWCYH---EQLENR---SF 59
            ::||...|....:|   |.||||.......:   |.....:.|.|:|.|..   .:|..|   |.
Mouse     5 DDILEHIGEFHLFQKQTFFLLALLSGAFTPI---YVGIVFLGFTPNHHCRSPGVAELSQRCGWSP 66

  Fly    60 AE-----IEKIYSQFEKPSCTRLEKIDEDGQNHT------LSRERCNR-----------WIYKYD 102
            ||     :..:.|..|....::..:.:.|....|      ||....||           |:  ||
Mouse    67 AEELNYTVPGLGSAGEVSFLSQCMRYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWV--YD 129

  Fly   103 FGYKSMNTELNWVCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGR---IRALILAN-WCGFLG 163
            ....|:.||.|.||..::...:.|||..||...|.:..|.|.||.||   :...||.| ..|.|.
Mouse   130 TPGSSIVTEFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRKFCLLVTILINAISGVLM 194

  Fly   164 DFSTIFAGSLTSFSISRFISGLAADANSYLMYILILEYVSPSLRNVGLNTVLGSFY----CLGLI 224
            ..|..:|..|    :.||:.||.:.|...:.||||.|:|     .:|....:|..|    .:||:
Mouse   195 AISPNYAWML----VFRFLQGLVSKAGWLIGYILITEFV-----GLGYRRTVGICYQIAFTVGLL 250

  Fly   225 GACWLAVWVGHWRIFLACSSVPLLLVTLFYFLVQESAQWLVTRNDVDGAIRRLERVAKINRRQV- 288
            ....:|..:.:||......::|.....|:::.:.||.:||:::|....|::.::.:||.|.:.|
Mouse   251 ILAGVAYALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNAKAMKIIKHIAKKNGKSVP 315

  Fly   289 -------ADKDFKDFRIYCEQHYRKDKNQEEHAKLLDMLKTPRMRSTAFKLLLIFIIIVPCYNTI 346
                   ||               :|...:.:...||:::||::|.....|:         ||..
Mouse   316 VSLQSLTAD---------------EDTGMKLNPSFLDLVRTPQIRKHTLILM---------YNWF 356

  Fly   347 ARNV--EGL-------GISPFIMFSLNALTLPPSGYLQGLLQDRMGRKATAVGWMAITGIFAVAA 402
            ..:|  :||       |.:.::.|..:||...|:.::..|..||:||:   ..| |::.:.|.||
Mouse   357 TSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRIGRR---YPW-AVSNMVAGAA 417

  Fly   403 GLVISQGSNRNVLLLVGLTMAARFGVSIADGASSQFSTELIPTSVRGRGVAV----VHVAGFAAS 463
            .|......:....|.:.:....|.|::||.......:.||.||.:|...|.|    ..:.|....
Mouse   418 CLASVFIPDDLQWLKITVACLGRMGITIAYEMVCLVNAELYPTYIRNLAVLVCSSMCDIGGIVTP 482

  Fly   464 FLSPYILHLGTYYKPAPSIILGLLFLSGAYVCLLLPETRNKKLPMSLAEGEEFGR 518
            ||   :..|...:...|.::..::.|....:.||||||:.|.||.::.:.|:..|
Mouse   483 FL---VYRLTDIWLEFPLVVFAVVGLVAGGLVLLLPETKGKALPETIEDAEKMQR 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	140/555 (25%)
		MFS	127..499	CDD:119392	100/400 (25%)
Slc22a2	NP_038695.1	2A0119	12..525	CDD:273328	142/557 (25%)
		MFS	125..492	CDD:119392	106/408 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843825
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950