Protein Alignment CG14855 and SLC22A31

DIOPT Version :9

• Sequence 1: NP_650390.2
• Gene: CG14855 / 41789
• FlyBaseID: FBgn0038260
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 436
• Identity: 115/436 - (26%)
• Similarity: 177/436 - (40%)
• Gaps: 58/436 - (13%)

  Fly   113 NW--VCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGR----IRALILANWCGFLGDFSTIFAG 171
            ||  ||.:.:|..:.|....:|.:.|.:..|...||.||    :.:|:|....|    .|...|.
Human     8 NWNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLG----ASEALAA 68

  Fly   172 SLTSFSISRFISGLAADANSYLMYILILEYVSPSLR-----NVGLNTVLGSFYCLGLIGACWLAV 231
            |..:..:.|.:.|.........:|:..||...|..|     ..||.:|:|:....|      ||.
Human    69 SFPTLLVLRLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPG------LAA 127

  Fly   232 WVGHWRIFLACSSVPLLLVTLFY---FLVQESAQWLVTRNDVDGAIRRLERVAKINRRQVADKDF 293
            .|..||:.....::...|:.||:   .|..||..||:....|..|.:.|.|.|:.:.....|...
Human   128 LVQDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPGDSSL 192

  Fly   294 KDFRIYCEQHYRKDKN-QEEHAKLLDMLKTPRMRST-------AFKLLLIFIIIVPCYNTIARNV 350
            ::..:..|......:: |..:...|.:|:|   |.|       .|..|:...|......::|..|
Human   193 EENSLATELTMLSARSPQPRYHSPLGLLRT---RVTWRNGLILGFSSLVGGGIRASFRRSLAPQV 254

  Fly   351 EGLGISPFIMFSLNALTLPPSGYLQGLLQDRMGRKATAVGWMAITGIFAVAAGLVISQGSNR--- 412
            ....:..|:...|.|..|.   :|. |..|..||:...:....:||:    |.|::..|:..
Human   255 PTFYLPYFLEAGLEAAALV---FLL-LTADCCGRRPVLLLGTMVTGL----ASLLLLAGAQYLPG 311

  Fly   413 -NVLLLVGLTMAARFGVSIADGASSQFSTELIPTSVRGRGVAVVHVAGFAASFLSPY-ILH--LG 473
             .||.|..|.:.|...||   ..||.|:.|:.||.:||.|:.:|..|||......|. .||  .|
Human   312 WTVLFLSVLGLLASRAVS---ALSSLFAAEVFPTVIRGAGLGLVLGAGFLGQAAGPLDTLHGRQG 373

  Fly   474 TYYKPAPSIILGLLFLSGAYVC-LLLPETRNKKLPMSLAEGEEFGR 518
            .:.:......|.:|    |.:| |||||:|::.||.||.:.:...|
Human   374 FFLQQVVFASLAVL----ALLCVLLLPESRSRGLPQSLQDADRLRR 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	110/423 (26%)
		MFS	127..499	CDD:119392	100/399 (25%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:421695	99/397 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153748
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.030