DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14855 and slc22a13a

DIOPT Version :9

Sequence 1:	NP_650390.2	Gene:	CG14855 / 41789	FlyBaseID:	FBgn0038260	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	XP_021322911.1	Gene:	slc22a13a / 100007819	ZFINID:	ZDB-GENE-070912-473	Length:	537	Species:	Danio rerio

Alignment Length:	551	Identity:	128/551 - (23%)
Similarity:	227/551 - (41%)	Gaps:	77/551 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DFEEILAKCGNSSRYQFVLLALYGYLMVVVSMHYFSQNVISFVPDHWCYHE-------------- 52
            :|.|||...|:...:|.:||....:..:::.....|........:|.|..:
Zfish     3 NFGEILEAIGDFGLFQKLLLFALCFPNLILPFQLSSLVFNHADTNHHCNTDWILKADPNLTKEEQ 67

  Fly    53 ------QLENRSFAEIEKIYSQFEKPSCTRLEKIDEDGQNHTLSRERC-NRWIYKYDFGYKSMNT 110
                  :|.:.||..     .|..||....|..|.|.|.|.|.:   | :.|::.......::.|
Zfish    68 LNLTLPRLSDGSFNP-----CQMYKPVDWNLSAIQEYGLNQTTT---CTDGWVHNDTIYEATIVT 124

  Fly   111 ELNWVCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGRIRA------LILANWCGFLGDFSTIF 169
            :.:.||:.....|..|::||.|.:.|.:.||...:..||.||      |:|         ..|:.
Zfish   125 DFDLVCENVNIFRGAQTVFFAGVLVGAILFGPFSESFGRKRATQIPMVLML---------IFTVV 180

  Fly   170 AGSLTSF---SISRFISGLAADANSYLMYILILEYVSPSLRNVG--LNTVLGSFYCLGLIGACWL 229
            .|...:|   .:|:||:|:..........||..|::..:.|:..  |:.||.:   ||.:....:
Zfish   181 TGLSPNFYVYLVSQFINGVGLGGFRINSIILASEWIGVAQRSYAACLSQVLAA---LGQVMFLAV 242

  Fly   230 AVWVGHWRIFLACSSVPLLLVTLFYFLVQESAQWLVTRNDVDGAIRRLERVAKINRRQVADKDFK 294
            ..:|..||:.....:.|:.:|.::.:.:.|||:||:.|.....|.:.:::.|.:|:|.|.:.
Zfish   243 VYFVRDWRLDQFIMAGPIGIVVIYIWFLPESARWLLDRGRTKDAKKLIQKAAAVNKRAVPES--- 304

  Fly   295 DFRIYCEQHYRKDKNQEEHA-KLLDMLKTPRMRSTAFKLLLIFIIIVPC-----YNTIARNVEGL 353
                 ..:...|:|..|:.. |:|       ..|...:...:.|....|     |.:::.||...
Zfish   305 -----LVEEVLKEKPVEKGGIKIL-------FGSRVLRKYFLAITFAWCALNLAYYSLSLNVGKF 357

  Fly   354 GISPFIMFSLNALTLPPSGYLQGLLQDRMGRKATAVGWMAITGIFAVAAGLVISQGSNRNVLLLV 418
            |:..|:...:..|:..|..:|.....:.:|||.:.:..:.:.|...:   |.::...|.::.:.|
Zfish   358 GLDIFLTQLIFGLSEIPVHFLCMWSLEVVGRKPSLIVSLVLGGCLCL---LTVAVPQNSSIAIAV 419

  Fly   419 GLTMAARFGVSIADGASSQFSTELIPTSVRGRGVAVVHVAGFAASFLSPYILHLGTYYKPAPSII 483
             |....||.::.|....:.:..||.|||:|.....:...|..|.|.|||.:..|..::...|.::
Zfish   420 -LATCGRFLMNAAGSVCNVYFQELFPTSIRQTATGLGSTAARAGSMLSPVVNMLEIFHFSIPMVV 483

  Fly   484 LGLLFLSGAYVCLLLPETRNKKLPMSLAEGE 514
            :..|.|:......||||||..:||.|..|.|
Zfish   484 ISSLALASGVTAFLLPETRRTELPASTEEAE 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	119/533 (22%)
CG14855	NP_650390.2	MFS	127..499	CDD:119392	88/388 (23%)
slc22a13a	XP_021322911.1	Sugar_tr	12..507	CDD:331684	119/533 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588888
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.950