Protein Alignment CG7362 and pykA

DIOPT Version :10

• Sequence 1: NP_650388.2
• Gene: CG7362 / 41787
• FlyBaseID: FBgn0038258
• Length: 793
• Species: Drosophila melanogaster
• Sequence 2: NP_416368.1
• Gene: pykA / 946527
• ECOCYCID: EG10803
• Length: 480
• Species: Escherichia coli
• Alignment Length: 490
• Identity: 135/490 - (27%)
• Similarity: 210/490 - (42%)
• Gaps: 144/490 - (29%)

  Fly    31 RLPLTSIICTIGPSSSQPEVLLNLIHAGMKVVRLDFSDGTHDCHCQAIQAARKAIAMYAEETGLP 95
            ||..|.|:.|:||::.:...|..:|.||..|||::||.|:.:.|.......|:..|.      |.
E. coli     4 RLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVREIAAK------LG 62

  Fly    96 RSLAIALDTKGPV------------------------------------INPQGVAADL------ 118
            |.:||..|.:||.                                    |:.:|:.||:
E. coli    63 RHVAILGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGKGEGDKEKVGIDYKGLPADVVPGDIL 127

  Fly   119 --------------------------------------------NAITEQDKLDLKFGADQKVDM 139
                                                        .|:||:||.|:|..|...||.
E. coli   128 LLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNKGINKLGGGLSAEALTEKDKADIKTAALIGVDY 192

  Fly   140 IFASFIRDAKALKEIRQAL--GACPSSEHIKIISKIESQQALAN---IDEIIRESDGIMVALGNM 199
            :..||.|..:.|...|:..  ..|.:    ||::|:|..:|:.:   :|:||..||.:|||.|::
E. coli   193 LAVSFPRCGEDLNYARRLARDAGCDA----KIVAKVERAEAVCSQDAMDDIILASDVVMVARGDL 253

  Fly   200 GNEIALEAVPLAQKSIVAKCNKVGKPVICANQMMNSMITKPRPTRAESSDVANAILDGCDALVLS 264
            |.||....:...||:::.:..::.:.||.|.|||.||||.|.|||||..|||||:|||.||::||
E. coli   254 GVEIGDPELVGIQKALIRRARQLNRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLS 318

  Fly   265 DETAKGKYPVQCVQCMARICAKVESVLWYESIQ----------NNLKSEVRIN---AADHISAVS 316
            .|||.|:||.:.|..|||:|...|.:   .||.          :|::..:.::   ||:|:..|:
E. coli   319 AETAAGQYPSETVAAMARVCLGAEKI---PSINVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVT 380

  Fly   317 TAIAEAATVSQAQAIVVASPCSIVSQMVSQMRPPCPIVLLTGCPHEAAQSL--LFRGVYPLLVKE 379
                         ||:..:.....:.|.|::....||..::  .||...:|  |:|||.|:....
E. coli   381 -------------AIITMTESGRTALMTSRISSGLPIFAMS--RHERTLNLTALYRGVTPVHFDS 430

  Fly   380 MVYG------SVNYCR----IMQSGLKILAKLDIL 404
            ...|      :||..|    :|...|.|:.:.|::
E. coli   431 ANDGVAAASEAVNLLRDKGYLMSGDLVIVTQGDVM 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7362	NP_650388.2	Pyruvate_Kinase	35..407	CDD:453956	133/486 (27%)
		PTZ00121	<476..>791	CDD:173412
pykA	NP_416368.1	PRK05826	3..469	CDD:235619	135/490 (28%)