Protein Alignment CG7362 and PYK2

DIOPT Version :9

• Sequence 1: NP_650388.2
• Gene: CG7362 / 41787
• FlyBaseID: FBgn0038258
• Length: 793
• Species: Drosophila melanogaster
• Sequence 2: NP_014992.3
• Gene: PYK2 / 854529
• SGDID: S000005874
• Length: 506
• Species: Saccharomyces cerevisiae
• Alignment Length: 517
• Identity: 167/517 - (32%)
• Similarity: 246/517 - (47%)
• Gaps: 115/517 - (22%)

  Fly    15 SQLDYQSRLQFQAPALRLPLTSIICTIGPSSSQPEVLLNLIHAGMKVVRLDFSDGTHDCHCQAIQ 79
            |:|...:.|:...|. :|..||||.||||.::..|.:..|..||:.::||:||.|:::.|...|:
Yeast     4 SRLQRLANLKIGTPQ-QLRRTSIIGTIGPKTNSCEAITALRKAGLNIIRLNFSHGSYEFHQSVIE 67

  Fly    80 AARKAIAMYAEETGLP-RSLAIALDTKGPVI---------------------------------- 109
            .|.|:      |...| |.||||||||||.|
Yeast    68 NAVKS------EQQFPGRPLAIALDTKGPEIRTGRTLNDQDLYIPVDHQMIFTTDASFANTSNDK 126

  Fly   110 -------------------------------------------------------NPQGVAADLN 119
                                                                   |......||.
Yeast   127 IMYIDYANLTKVIVPGRFIYVDDGILSFKVLQIIDESNLRVQAVNSGYIASHKGVNLPNTDVDLP 191

  Fly   120 AITEQDKLDLKFGADQKVDMIFASFIRDAKALKEIRQALGACPSSEHIKIISKIESQQALANIDE 184
            .::.:|..||:||....:.::||||||.::.:..||:|||:  ..:.||||||||:||.|.|.||
Yeast   192 PLSAKDMKDLQFGVRNGIHIVFASFIRTSEDVLSIRKALGS--EGQDIKIISKIENQQGLDNFDE 254

  Fly   185 IIRESDGIMVALGNMGNEIALEAVPLAQKSIVAKCNKVGKPVICANQMMNSMITKPRPTRAESSD 249
            |:..:||:|:|.|::|.||....|...||.::||||..|||||||.||::||...|||||||.||
Yeast   255 ILEVTDGVMIARGDLGIEILAPEVLAIQKKLIAKCNLAGKPVICATQMLDSMTHNPRPTRAEVSD 319

  Fly   250 VANAILDGCDALVLSDETAKGKYPVQCVQCMARICAKVESVLWYESIQNNLKSEVRINAADHISA 314
            |.||:|||.|.::||.|||||.|||..|..||......||.:.:.::.::|:     :|....::
Yeast   320 VGNAVLDGADCVMLSGETAKGDYPVNAVNIMAATALIAESTIAHLALYDDLR-----DATPKPTS 379

  Fly   315 VSTAIAEAATVS----QAQAIVVASPCSIVSQMVSQMRPPCPIVLLTGCPHEAAQSLLFRGVYPL 375
            .:..:|.|||.:    ..:||||.|.....::::|:.||.|||:|:|.....|..:.|:|||:|.
Yeast   380 TTETVAAAATAAILEQDGKAIVVLSTTGNTARLLSKYRPSCPIILVTRHARTARIAHLYRGVFPF 444

  Fly   376 LV--KEMVYGSVNYCRIMQSGLKILAKLDILKAGQRGTLVLVNAMS---ADKLTFRLFTFAQ 432
            |.  |.:.....:..|.::.|:::.....::..|.  |:|.:....   ....|.|:.|..|
Yeast   445 LYEPKRLDDWGEDVHRRLKFGVEMARSFGMVDNGD--TVVSIQGFKGGVGHSNTLRISTVGQ 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7362	NP_650388.2	Pyruvate_Kinase	35..407	CDD:304951	155/467 (33%)
		pyruv_kin	35..391	CDD:273424	154/451 (34%)
PYK2	NP_014992.3	Pyruvate_Kinase	20..502	CDD:238178	161/496 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343746
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100258
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.700