Protein Alignment CG7362 and Pkm

DIOPT Version :9

• Sequence 1: NP_650388.2
• Gene: CG7362 / 41787
• FlyBaseID: FBgn0038258
• Length: 793
• Species: Drosophila melanogaster
• Sequence 2: XP_011240976.2
• Gene: Pkm / 18746
• MGIID: 97591
• Length: 604
• Species: Mus musculus
• Alignment Length: 496
• Identity: 174/496 - (35%)
• Similarity: 252/496 - (50%)
• Gaps: 108/496 - (21%)

  Fly    17 LDYQSRLQFQAPALRLPLTSIICTIGPSSSQPEVLLNLIHAGMKVVRLDFSDGTHDCHCQAIQAA 81
            |::..||...:..:....|.|||||||:|...|:|..:|.:||.|.||:||.|||:.|.:.|:..
Mouse   100 LEHMCRLDIDSAPITARNTGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNV 164

  Fly    82 RKAIAMYAEETGLPRSLAIALDTKGPVI------------------------------------- 109
            |:|...:|.:..|.|.:|:|||||||.|
Mouse   165 REATESFASDPILYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENI 229

  Fly   110 -----------------------------------------------------NPQGVAADLNAI 121
                                                                 |..|.|.||.|:
Mouse   230 LWLDYKNICKVVEVGSKIYVDDGLISLQVKEKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAV 294

  Fly   122 TEQDKLDLKFGADQKVDMIFASFIRDAKALKEIRQALGACPSSEHIKIISKIESQQALANIDEII 186
            :|:|..|||||.:|.|||:||||||.|..:.|:|:.||  ...::||||||||:.:.:...|||:
Mouse   295 SEKDIQDLKFGVEQDVDMVFASFIRKAADVHEVRKVLG--EKGKNIKIISKIENHEGVRRFDEIL 357

  Fly   187 RESDGIMVALGNMGNEIALEAVPLAQKSIVAKCNKVGKPVICANQMMNSMITKPRPTRAESSDVA 251
            ..|||||||.|::|.||..|.|.||||.::.:||:.|||||||.||:.|||.||||||||.||||
Mouse   358 EASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVA 422

  Fly   252 NAILDGCDALVLSDETAKGKYPVQCVQCMARICAKVESVLWYESIQNNLKSEVRINAADHISAVS 316
            ||:|||.|.::||.|||||.||::.|:....|..:.|:.:::..:...|:....| .:|...|.:
Mouse   423 NAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPI-TSDPTEAAA 486

  Fly   317 TAIAEAATVSQAQAIVVASPCSIVSQMVSQMRPPCPIVLLTGCPHEAAQSLLFRGVYPLLVKEMV 381
            ....||:....:.||:|.:.....:..|::.||..||:.:|..|..|.|:.|:||::|:|.|:.|
Mouse   487 VGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAV 551

  Fly   382 YGS----VNYCRIMQSGLKILAKLDILKAG---QRGTLVLV 415
            ..:    |:        |::...:|:.||.   ::|.:|:|
Mouse   552 LNAWAEDVD--------LRVNLAMDVGKARGFFKKGDVVIV 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7362	NP_650388.2	Pyruvate_Kinase	35..407	CDD:304951	167/465 (36%)
		pyruv_kin	35..391	CDD:273424	164/449 (37%)
Pkm	XP_011240976.2	Pyruvate_Kinase	115..603	CDD:238178	171/481 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D219692at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100258
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.780