DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eff and UBE2R2

DIOPT Version :9

Sequence 1:	NP_001262578.1	Gene:	eff / 41785	FlyBaseID:	FBgn0011217	Length:	147	Species:	Drosophila melanogaster
Sequence 2:	NP_060281.2	Gene:	UBE2R2 / 54926	HGNCID:	19907	Length:	238	Species:	Homo sapiens

Alignment Length:	157	Identity:	51/157 - (32%)
Similarity:	82/157 - (52%)	Gaps:	20/157 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KRINKELQDLGRDPPAQCSAGPVGD-DLFHWQATIMGPPDSPYQGGVFFLTIHFPTDYPFKPPKV 67
            |.:..||:.|..:|........|.: ||::|:..|.|||::.|:||.|...|.||.|||:.||..
Human    11 KALMLELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPIDYPYSPPTF 75

  Fly    68 AFTTRIYHPNINSNGSICLDILR-------------SQWSPALTISKVLLSICSLLCDPNPDDPL 119
            .|.|:::||||..||.:|:.||.             .:|:|...:..:|||:.|||.:||...|.
Human    76 RFLTKMWHPNIYENGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPA 140

  Fly   120 VPEIARIYKTDRE------KYNELARE 140
            ..:.:.:::..|:      :|.|:.|:
Human   141 NVDASVMFRKWRDSKGKDKEYAEIIRK 167

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eff	NP_001262578.1	UBCc	1..146	CDD:412187	51/157 (32%)
UBE2R2	NP_060281.2	UBCc	11..169	CDD:238117	51/157 (32%)
UBE2R2	NP_060281.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	194..238
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910