DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG7530 and PAQR8

DIOPT Version :9

Sequence 1:NP_650387.1 Gene:CG7530 / 41784 FlyBaseID:FBgn0038256 Length:351 Species:Drosophila melanogaster
Sequence 2:NP_588608.1 Gene:PAQR8 / 85315 HGNCID:15708 Length:354 Species:Homo sapiens


Alignment Length:314 Identity:69/314 - (21%)
Similarity:114/314 - (36%) Gaps:95/314 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 PNILGHGPNYDDKLSKFKWLCNFDDAPSHLKFNPYIRRGYRTFLPSTKMCLQSIFWWTNETINIW 121
            |.||      :|.|.|........|.|...: .||||.|||......:....|:|...||.:|:|
Human    23 PKIL------EDGLPKMPCTVPETDVPQLFR-EPYIRTGYRPTGHEWRYYFFSLFQKHNEVVNVW 80

  Fly   122 SHLAGCILFIGLTIFDLQFLRL-------HASLSDQVLVVCLL--VCFCLCMLMSAIYHIFSCKS 177
            :||...:..:      |:|...       .||.....|::.:|  :.:..|.|::   |:...||
Human    81 THLLAALAVL------LRFWAFAEAEALPWASTHSLPLLLFILSSITYLTCSLLA---HLLQSKS 136

  Fly   178 EEHYELFLSVDFLGISLSLVAIYISGMYYA--------FW------------------CHT---- 212
            |..:..|..||::|:|:......::..:|:        ||                  |:.    
Human   137 ELSHYTFYFVDYVGVSVYQYGSALAHFFYSSDQAWYDRFWLFFLPAAAFCGWLSCAGCCYAKYRY 201

  Fly   213 -----FLRTLYSTIALGM-FALAIAVQIPRLNVSMNGKVAVLLLWSAYGIIPLGHWAVA---MGG 268
                 .:|.:...:..|: |.|.|:                          |:.| .||   :.|
Human   202 RRPYPVMRKICQVVPAGLAFILDIS--------------------------PVAH-RVALCHLAG 239

  Fly   269 LENELVRLMVPRIVLMYLLCLVAFVFYAAKIPERWFTGKVDFVGHSHNWWHLII 322
            .:.:.....    .|..|..||:..|::..:||::|.|..|.|||.|..:|..:
Human   240 CQEQAAWYH----TLQILFFLVSAYFFSCPVPEKYFPGSCDIVGHGHQIFHAFL 289

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7530NP_650387.1 HlyIII 111..329 CDD:281059 53/260 (20%)
PAQR8NP_588608.1 HlyIII 70..297 CDD:308575 53/260 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1272
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1524940at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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