DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7530 and IZH1

DIOPT Version :9

Sequence 1:	NP_650387.1	Gene:	CG7530 / 41784	FlyBaseID:	FBgn0038256	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_010780.1	Gene:	IZH1 / 852102	SGDID:	S000002900	Length:	316	Species:	Saccharomyces cerevisiae

Alignment Length:	266	Identity:	80/266 - (30%)
Similarity:	129/266 - (48%)	Gaps:	22/266 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 KFKWLCNFDDAPSHLKFNPYIRRGYRTFLPSTKMCLQSIFWWTNETINIWSHLAGCILF----IG 132
            |.|.|.|||:.|...|.|..|..||.....|.|.||.|:|:|.|||:||::||...|::    |.
Yeast    36 KQKLLHNFDELPEWQKDNDKILTGYVRETLSWKKCLYSLFYWNNETVNIYTHLVPAIVYFVFAIT 100

  Fly   133 LTIFDLQFLRLHASLSDQVLVVCLLVCFCLCMLMSAIYHIFSCKSEEHYELFLSVDFLG----IS 193
            ||.:.|..:....|.||..::...|:....|::.|:.:|.....||:....:..:|:||    ||
Yeast   101 LTNYFLIPVFPSTSWSDYTVINIFLMGAFSCLMCSSCFHCMKQHSEKQSNFWSKLDYLGIISLIS 165

  Fly   194 LSLVAIYISGMYYAFWCHTFLRTLYS--TIALGMFALAIAVQIPRLNVS--MNGKVAVLLLWSAY 254
            .|::.|    :|:.::.|....:|::  |:.|..|. .:.|...:.|.|  ...:....:|:...
Yeast   166 CSMIPI----IYFGYFDHISYFSLFTIVTLVLATFC-TVCVLHDKFNTSTFRPFRAMFFILFGFS 225

  Fly   255 GIIPL--GHWAVAMGGLENELVRLMVPRIVLMYLLCLVAFVFYAAKIPERWFTGKVDFVGHSHNW 317
            |::||  |.:..   |::..|.|:.|..:....|..:...|.|..:|||....||.||.|.||..
Yeast   226 GLLPLTTGFFKF---GIQGVLNRIKVSFVFWEALFYISGAVIYGFRIPETLAPGKFDFFGSSHQI 287

  Fly   318 WHLIIV 323
            :|:::|
Yeast   288 FHIMVV 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7530	NP_650387.1	HlyIII	111..329	CDD:281059	63/227 (28%)
IZH1	NP_010780.1	HlyIII	75..300	CDD:397239	63/227 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53658
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR20855
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920