DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7530 and Paqr3

DIOPT Version :9

Sequence 1:	NP_650387.1	Gene:	CG7530 / 41784	FlyBaseID:	FBgn0038256	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_001346839.1	Gene:	Paqr3 / 231474	MGIID:	2679683	Length:	311	Species:	Mus musculus

Alignment Length:	286	Identity:	107/286 - (37%)
Similarity:	169/286 - (59%)	Gaps:	27/286 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 LCNFDDAPSHLKFNPYIRRGYRTFLPSTKMCLQSIFWWTNETINIWSHLAGCILFIGLTIFDLQF 140
            |..::..|..||.||||..|||.:||| ::|::|:|..:|||:||||||.|..||..|.|:|:..
Mouse    30 LYTYEQIPVSLKDNPYITDGYRAYLPS-RLCIKSLFILSNETVNIWSHLLGFFLFFTLGIYDMTS 93

  Fly   141 LRLHASLSDQVLVVC--LLVCFCLCMLMSAIYHIFSC-KSEEHYELFLSVDFLGISLSLVAIYIS 202
            :...||.|.:..|:|  .|.||.:|||.|..||:||| :||:....::::|:.|||:.::..|:|
Mouse    94 VLPSASASREDFVICSICLFCFQVCMLCSVGYHLFSCHRSEKTCRRWMALDYAGISIGILGCYVS 158

  Fly   203 GMYYAFWCHTFLRTLYSTIALGMFALAIAVQI-------------PRLNVSMNGKVAVLLLWSAY 254
            |::|||:|:.:.|.:|....|.|.......||             |.:..|::|          |
Mouse   159 GVFYAFYCNNYWRQVYLITVLAMILAVFFAQIHPSYLTQQWQRLRPIIFCSVSG----------Y 213

  Fly   255 GIIPLGHWAVAMGGLENELVRLMVPRIVLMYLLCLVAFVFYAAKIPERWFTGKVDFVGHSHNWWH 319
            |:||..||....||:...:|:...||:::||::.|:||:||.:|:|||:|.|:::::|.||..||
Mouse   214 GVIPTLHWVWLNGGVSAPIVQDFAPRVIVMYVIALLAFLFYISKVPERYFPGQLNYLGSSHQIWH 278

  Fly   320 LIIVAAFYHWHNTGLVYAEYRLNNGC 345
            ::.|...|.||.:.:...:||.:..|
Mouse   279 VLAVVMLYWWHQSTVYVMQYRHSKPC 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7530	NP_650387.1	HlyIII	111..329	CDD:281059	86/233 (37%)
Paqr3	NP_001346839.1	Golgi targeting. /evidence=ECO:0000250	61..71		4/9 (44%)
		HlyIII	64..283	CDD:367292	84/228 (37%)
		Golgi targeting. /evidence=ECO:0000250	299..303		1/3 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837099
Domainoid	1	1.000	170	1.000	Domainoid score	I3780
eggNOG	1	0.900	-	-		E1_COG1272
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H71077
Inparanoid	1	1.050	218	1.000	Inparanoid score	I3578
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53658
OrthoDB	1	1.010	-	-		D1524940at2759
OrthoFinder	1	1.000	-	-		FOG0005518
OrthoInspector	1	1.000	-	-		oto92340
orthoMCL	1	0.900	-	-		OOG6_106474
Panther	1	1.100	-	-	LDO	PTHR20855
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4360
SonicParanoid	1	1.000	-	-		X3936
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800