Protein Alignment CG7530 and PAQR3

DIOPT Version :9

• Sequence 1: NP_650387.1
• Gene: CG7530 / 41784
• FlyBaseID: FBgn0038256
• Length: 351
• Species: Drosophila melanogaster
• Sequence 2: NP_001035292.1
• Gene: PAQR3 / 152559
• HGNCID: 30130
• Length: 311
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 106/276 - (38%)
• Similarity: 169/276 - (61%)
• Gaps: 7/276 - (2%)

  Fly    76 LCNFDDAPSHLKFNPYIRRGYRTFLPSTKMCLQSIFWWTNETINIWSHLAGCILFIGLTIFDLQF 140
            |..::..|..||.||||..|||.:||| ::|::|:|..:|||:||||||.|..||..|.|:|:..
Human    30 LYTYEQIPGSLKDNPYITDGYRAYLPS-RLCIKSLFILSNETVNIWSHLLGFFLFFTLGIYDMTS 93

  Fly   141 LRLHASLSDQVLVVC--LLVCFCLCMLMSAIYHIFSC-KSEEHYELFLSVDFLGISLSLVAIYIS 202
            :...||.|.:..|:|  .|.||.:|||.|..||:||| :||:....::::|:.|||:.::..|:|
Human    94 VLPSASASREDFVICSICLFCFQVCMLCSVGYHLFSCHRSEKTCRRWMALDYAGISIGILGCYVS 158

  Fly   203 GMYYAFWCHTFLRTLYSTIALGMFALAIAVQI-PRLNVSMNGKVAVLLLW--SAYGIIPLGHWAV 264
            |::|||:|:.:.|.:|....|.|.......|| |........::..::..  |.||:||..||..
Human   159 GVFYAFYCNNYWRQVYLITVLAMILAVFFAQIHPNYLTQQWQRLRSIIFCSVSGYGVIPTLHWVW 223

  Fly   265 AMGGLENELVRLMVPRIVLMYLLCLVAFVFYAAKIPERWFTGKVDFVGHSHNWWHLIIVAAFYHW 329
            ..||:...:|:...||:::||::.|:||:||.:|:|||:|.|:::::|.||..||::.|...|.|
Human   224 LNGGIGAPIVQDFAPRVIVMYMIALLAFLFYISKVPERYFPGQLNYLGSSHQIWHILAVVMLYWW 288

  Fly   330 HNTGLVYAEYRLNNGC 345
            |.:.:...:||.:..|
Human   289 HQSTVYVMQYRHSKPC 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7530	NP_650387.1	HlyIII	111..329	CDD:281059	85/223 (38%)
PAQR3	NP_001035292.1	Golgi targeting	61..71		4/9 (44%)
		HlyIII	64..283	CDD:308575	83/218 (38%)
		Golgi targeting	299..303		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147155
Domainoid	1	1.000	171	1.000	Domainoid score	I3754
eggNOG	1	0.900	-	-		E1_COG1272
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H71077
Inparanoid	1	1.050	219	1.000	Inparanoid score	I3583
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53658
OrthoDB	1	1.010	-	-		D1524940at2759
OrthoFinder	1	1.000	-	-		FOG0005518
OrthoInspector	1	1.000	-	-		oto88774
orthoMCL	1	0.900	-	-		OOG6_106474
Panther	1	1.100	-	-	LDO	PTHR20855
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4360
SonicParanoid	1	1.000	-	-		X3936
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800