Protein Alignment kibra and MAGIX

DIOPT Version :10

• Sequence 1: NP_001034055.1
• Gene: kibra / 41783
• FlyBaseID: FBgn0262127
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_079135.3
• Gene: MAGIX / 79917
• HGNCID: 30006
• Length: 334
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 54/265 - (20%)
• Similarity: 94/265 - (35%)
• Gaps: 81/265 - (30%)

  Fly   378 LLIQEKEKLLNDLNSISLK---SRSEEEKRVIHQTRHKLEEDLKEAYEANNTCVANRLRFHEEKQ 439
            |.::.|| .::.|:|..::   ||......|.|:.:|:..|          ||.|       ..|
Human    59 LRLRRKE-AVSVLDSADIEVTDSRLPHATIVDHRPQHRWLE----------TCNA-------PPQ 105

  Fly   440 LLLDKLQEALKSTKLLEERLKSFSSESTFSISSGSSLGSLSTASSKSALSFTDIYIDPFAVDSP- 503
            |:..|.:.|.|.::.        |...:..:..|.:...|:....:.....|.:.:.....|.|
Human   106 LIQGKARSAPKPSQA--------SGHFSVELVRGYAGFGLTLGGGRDVAGDTPLAVRGLLKDGPA 162

  Fly   504 -----IDVVDL-----RRRSQRLFQQHQQQRL-----------------HPVHP--VLQQQQSA- 538
                 ::|.||     ...:|.|......:|:                 ||..|  |.:.::..
Human   163 QRCGRLEVGDLVLHINGESTQGLTHAQAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRKGVV 227

  Fly   539 -------------EVTLSPRSSLSM-ETPPA-SPMKYNAGA-DQTPQALKEEPTYANALPAPPAY 587
                         |||.|..||.|: :.||: :.:|...|: :.:|:|..:.||.     :||..
Human   228 PSWPDRSPDPGGPEVTGSRSSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGPTV-----SPPER 287

  Fly   588 TAPPP 592
            .|..|
Human   288 RAEDP 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kibra	NP_001034055.1	WW	57..87	CDD:238122
		WW	103..132	CDD:459800
		C2_Kibra	693..813	CDD:176062
MAGIX	NP_079135.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		PDZ5_MAGI-1_3-like	123..207	CDD:467217	11/83 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..306		23/89 (26%)