Protein Alignment kibra and Smurf2

DIOPT Version :10

• Sequence 1: NP_001034055.1
• Gene: kibra / 41783
• FlyBaseID: FBgn0262127
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_079757.2
• Gene: Smurf2 / 66313
• MGIID: 1913563
• Length: 748
• Species: Mus musculus
• Alignment Length: 220
• Identity: 48/220 - (21%)
• Similarity: 88/220 - (40%)
• Gaps: 39/220 - (17%)

  Fly    37 QQQQHTHHQQQQQHHSDFPLPDGWDIAKDFDGKTYYIDHINKKTTWLDPRDCYTKPQTFEDCVGD 101
            :.|:|.::..:...|:...||:|::......|:.|::......:||.|||    .|:...:...:
Mouse   234 RSQRHRNYMSRTHLHTPPDLPEGYEQRTTQQGQVYFLHTQTGVSTWHDPR----VPRDLSNINCE 294

  Fly   102 E---LPMGWEESYDPNIGPYYINHLAQSTQLEDPR---------QEWKTVQEQMLSDYLSAAQDQ 154
            |   ||.|||.........|:::|..::||..|||         .....:::|.....:....|.
Mouse   295 ELGPLPPGWEIRNTATGRVYFVDHNNRTTQFTDPRLSANLHLVLNRQNQLKDQQQQQVVPLCPDD 359

  Fly   155 LE------NKREM---FDVKQQRLLWAQEEYNHLKLAASRSSLCSSS-SSMSRHDPELLRADLML 209
            .|      .||::   ..:.:|.|...|.:..|.::..||..:...| ..:.:..|:.|...||:
Mouse   360 TECLTVPRYKRDLVQKLKILRQELSQQQPQAGHCRIEVSREEIFEESYRQVMKMRPKDLWKRLMI 424

  Fly   210 -------------ARERVHQLKQEL 221
                         |||.::.|..|:
Mouse   425 KFRGEEGLDYGGVAREWLYLLSHEM 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kibra	NP_001034055.1	WW	57..87	CDD:238122	8/29 (28%)
		WW	103..132	CDD:459800	9/28 (32%)
		C2_Kibra	693..813	CDD:176062
Smurf2	NP_079757.2	C2_Smurf-like	13..137	CDD:176028
		HUL4	<159..745	CDD:227354	48/220 (22%)