back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kibra and wwp2

DIOPT Version :9

Sequence 1:	NP_001034055.1	Gene:	kibra / 41783	FlyBaseID:	FBgn0262127	Length:	1288	Species:	Drosophila melanogaster
Sequence 2:	XP_005163228.1	Gene:	wwp2 / 564527	ZFINID:	ZDB-GENE-000607-82	Length:	867	Species:	Danio rerio

Alignment Length:	488	Identity:	95/488 - (19%)
Similarity:	170/488 - (34%)	Gaps:	168/488 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 RPQQQQQQHHHHHQQQQQQQHTHHQQQQQHHSDFP------------LPDGWDIAKDFDGKTYYI 73
            ||..:..:::...|.|:.|.....||..|.:...|            ||.||:..:| :|:.||:
Zfish   356 RPTAESVRNYEQWQSQRSQLQGAMQQFNQRYLYQPSGAVVENDPLGALPPGWEKRQD-NGRVYYV 419

  Fly    74 DHINKKTTWLDPRDCYTKPQTFEDCVGDELPMGWEESYDPNIGPYYINHLAQSTQLEDPRQEWKT 138
            :|..:.|.|.|||   |:....|    ..||.|||..|......|:::|.:::|..:|||..:::
Zfish   420 NHNTRTTQWEDPR---TQGMIQE----PPLPPGWEMKYTAEGVRYFVDHNSRTTTFKDPRPGFES 477

  Fly   139 VQEQMLSDYLSAAQDQLENKREMFDVKQQRLLWAQEEY----------NHLKLAASRSSLCSSS- 192
            ...|..|   ..|.|             :...|...::          :|:|::.||.:|...|
Zfish   478 GSRQGGS---PGAYD-------------RSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSF 526

  Fly   193 ---SSMSRHDPELLRADLM-------------LARERVHQLKQELTHITNDISYTERGMNTLYSV 241
               .:|..:|   ||..|.             :|||....|..|:             :|.:|.:
Zfish   527 QQIMNMKPYD---LRRRLYIIMRGEEGLDYGGIAREWFFLLSHEV-------------LNPMYCL 575

  Fly   242 GEKINARENGCYDIAEVHAIREEMLKVHKSLVSGEKVREELMRSLVQIKNELGRQQISEENSDLA 306
            .| ...:.|.|..|....:|..:.|...:.:
Zfish   576 FE-YAGKNNYCLQINPASSINPDHLTYFRFI---------------------------------- 605

  Fly   307 SPFDRVCVASQTDLCGSSGENLNGGARFAEMAKTKWQYAE------WRKHIKKLQQQLADHVERI 365
                                     .||..||....::.:      :.|.:...:..|.| :|.|
Zfish   606 -------------------------GRFIAMALYHGKFIDTGFTLPFYKRMLNKKPTLKD-LESI 644

  Fly   366 EPGQLESDKDRILLIQEKEKLLNDLNSISLKSRSEEEKRVIHQ-TRHKLEEDLKEAYEANNTCVA 429
            :|....|    |:.::|     |||....::....::..::.: |.|:|::|.:
Zfish   645 DPEFYNS----IMWVKE-----NDLEECGVELYFAQDMEILGKVTTHQLKDDGE----------- 689

  Fly   430 NRLRFHEEKQLLLDKLQEALKSTKLLEERLKSF 462
            |.|...:.|:..:..|.: .:.|:.:||:.|:|
Zfish   690 NELVTQDNKEEYIGLLTD-WRFTRGVEEQTKAF 721

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.