DRSC/TRiP Functional Genomics Resources

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Protein Alignment kibra and bag3

DIOPT Version :9

Sequence 1:NP_001034055.1 Gene:kibra / 41783 FlyBaseID:FBgn0262127 Length:1288 Species:Drosophila melanogaster
Sequence 2:NP_001003533.1 Gene:bag3 / 445139 ZFINID:ZDB-GENE-040801-40 Length:459 Species:Danio rerio


Alignment Length:562 Identity:103/562 - (18%)
Similarity:167/562 - (29%) Gaps:245/562 - (43%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 PLPDGWDIAKD-FDGKTYYIDHINKKTTWLDPRDCYTKPQTFEDCVGDELPMGWEESYDPNIGPY 118
            |||.||:|..| ..|..:::||.|:.|||.|||....|..:....:..|.|....::        
Zfish     6 PLPPGWEIKIDPQTGWPFFVDHNNRTTTWNDPRHDTKKIFSNGPSMSPETPQDMHKT-------- 62

  Fly   119 YINHLAQST------------QLEDPR-QEWKT-------VQEQMLSDYLSAAQDQLENKREMFD 163
            :||.:.|..            :..:|| |::.:       ||:.:.:|..:.:.....:.|....
Zfish    63 FINEMRQPMLRQGYIPIPVCHENPEPRLQQYPSFSYIHPAVQQNLRTDGRTPSPTPAAHCRPRSP 127

  Fly   164 VKQQRLLWAQEEYNHLKLAASRSSLCSSSSSMSRHDPELLRADLMLARERVHQ----LKQELTHI 224
            |:                  :.|..|||.|..| |.||..:.      :..||    |.|:    
Zfish   128 VQ------------------TPSEACSSCSPTS-HGPEGYQP------QGTHQQISGLHQQ---- 163

  Fly   225 TNDISYTERGMNTLYSVGEKINARENGCYDIAEVHAIREEMLKVHKSLVSGEKVREELMRSLVQI 289
                   .|..||         ....|...|..:|.....:|....| .|....||::.|..|.|
Zfish   164 -------PRSSNT---------GLRAGYIPIPVIHEGAGGVLPSQLS-QSSHPTREKIYREQVPI 211

  Fly   290 KNELGRQQISEENSDLASPFDRVCVASQTDLCGSSGENLNGGARFAEMAKTKWQYAEWRKHIKKL 354
                   ||.:..:  |||. :|.:.:|:.:                ||:...:..:.::||   
Zfish   212 -------QIQQNRA--ASPI-QVPLRAQSPV----------------MAQIMGERPQMQQHI--- 247

  Fly   355 QQQLADHVERIEPGQLESDKDRILLIQEKEKLLNDLNSISLKSRSEEEKRVIHQTRHKLEEDLKE 419
                 .|.  ..|.::|...:.|:.:...|        :.::..||..:::.||           
Zfish   248 -----GHT--AIPSKIEHPVEEIIRVPTFE--------VPIQRVSEVPQQIHHQ----------- 286

  Fly   420 AYEANNTCVANRLRFHEEKQLLLDKLQEALKSTKLLEERLKSFSSESTFSISSGSSLGSLSTASS 484
                                                                             
Zfish   287 ----------------------------------------------------------------- 286

  Fly   485 KSALSFTDIYIDPFAVDSPIDVVDLRRRSQRLFQQHQQQRLHPVHPVLQQQQSAEVT--LSPRSS 547
                              |:              |.|||      |..|.|..|:.:  :|..|:
Zfish   287 ------------------PV--------------QQQQQ------PTQQPQPKAQPSPQVSETSN 313

  Fly   548 LSMETPPASPMKYNAGADQTPQ-----ALKEEPTYANALPAP 584
            ::::.||| |......|.||||     .|:.|.|....|..|
Zfish   314 ITIQVPPA-PEPQETAAPQTPQEVPSSQLQPEETLEQDLSHP 354

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kibraNP_001034055.1 WW 57..87 CDD:238122 14/30 (47%)
WW 103..132 CDD:278809 4/40 (10%)
C2_Kibra 693..813 CDD:176062
bag3NP_001003533.1 WW 6..38 CDD:197736 15/31 (48%)
BAG 358..432 CDD:214591
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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