DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kibra and CG3356

DIOPT Version :9

Sequence 1:	NP_001034055.1	Gene:	kibra / 41783	FlyBaseID:	FBgn0262127	Length:	1288	Species:	Drosophila melanogaster
Sequence 2:	NP_611896.1	Gene:	CG3356 / 37876	FlyBaseID:	FBgn0034989	Length:	1122	Species:	Drosophila melanogaster

Alignment Length:	304	Identity:	67/304 - (22%)
Similarity:	112/304 - (36%)	Gaps:	103/304 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   676 DSGVFEASRAH----LPRKEL------AQVQIGLKYLKQEGVLVVSLERANNLLALWTASADNSQ 730
            |:.:.:.|.:|    :|.:.|      :.||   :|:|.|.||...:||....|.     |.|..
  Fly   145 DTCLLQLSLSHTAQAIPLRMLETFTTVSSVQ---QYMKDEAVLFQYMERVFGFLI-----ARNYF 201

  Fly   731 VYLRAALLPNSLTSIRTKALGDFQKPVFNDTFAVPITLD----KLLTKSLQVTVVTMTGQK---- 787
            |.||             :.|.|...|:..:|...|..|.    :||.:.|:|......|.:
  Fly   202 VRLR-------------RLLDDKCPPLDGETLHAPSPLAEALLQLLLRPLEVAKRASAGGQMSSM 253

  Fly   788 ---------EEIIGTVQISMAEFNPEDSTLKWYNVLSSKFIPSFE-SLDIP------STSAAAAA 836
                     .:|:.|         |....|:::      .:|.|. ::|.|      |...|..:
  Fly   254 SMAVCRNFTRDILAT---------PHTDPLRYF------VLPCFALNVDFPFDLLMRSLYDALES 303

  Fly   837 AAVAASNAPNPGNN-------------REESSDESTITSS-------QTSTLTRNQAPCMELQEQ 881
            |..|.|::.:...:             |.:|...|.:.:|       |.:||  :|:|.:.:..:
  Fly   304 AGPAESDSTSSRRSFLFYGVETGHKTTRMDSIFSSFLLNSLMVLDRRQLATL--HQSPLLVIYVR 366

  Fly   882 MAAELLG----------LGPLNEP-ECSDDDDDDEEEELDDKQL 914
            :.||::.          .|..|.| ...|.|||.||.|.:|::|
  Fly   367 LIAEMMPNILQLPKSTLRGHANAPHRHRDGDDDSEESEDEDEEL 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kibra	NP_001034055.1	WW	57..87	CDD:238122
		WW	103..132	CDD:278809
		C2_Kibra	693..813	CDD:176062	30/136 (22%)
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033
CG3356	NP_611896.1	HECTc	788..1119	CDD:214523
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900