DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kibra and yki

DIOPT Version :9

Sequence 1:	NP_001034055.1	Gene:	kibra / 41783	FlyBaseID:	FBgn0262127	Length:	1288	Species:	Drosophila melanogaster
Sequence 2:	NP_001350857.1	Gene:	yki / 37851	FlyBaseID:	FBgn0034970	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	223	Identity:	52/223 - (23%)
Similarity:	75/223 - (33%)	Gaps:	88/223 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPNLQQTASQSQHHLHPHHLR----PQQQQQQHH-------------HHHQQQQQQ--------- 39
            :|.||...|.....|..||.|    |...||.::             :.:...|||
  Fly   145 IPQLQIQPSPQHSRLAIHHSRARSSPASLQQNYNVRARSDAAAANNPNANPSSQQQPAGPTFPEN 209

  Fly    40 -------------------------------QHTHHQQQQQHHSDFP---------LPDGWDIAK 64
                                           ..|.|::|:.:....|         ||.||:.||
  Fly   210 SAQEFPSGAPASSAIDLDAMNTCMSQDIPMSMQTVHKKQRSYDVISPIQLNRQLGALPPGWEQAK 274

  Fly    65 DFDGKTYYIDHINKKTTWLDPRDCY-------------------TKPQTFEDCVGDE---LPMGW 107
            ..||:.||::|..|.|.|.|||..|                   |..||....:.:.   ||.||
  Fly   275 TNDGQIYYLNHTTKSTQWEDPRIQYRQQQQILMAERIKQNDVLQTTKQTTTSTIANNLGPLPDGW 339

  Fly   108 EESYDPNIGPYYINHLAQSTQLEDPRQE 135
            |::...:...|:|||:.::|...|||.:
  Fly   340 EQAVTESGDLYFINHIDRTTSWNDPRMQ 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kibra	NP_001034055.1	WW	57..87	CDD:238122	15/29 (52%)
		WW	103..132	CDD:278809	10/28 (36%)
		C2_Kibra	693..813	CDD:176062
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354	34/107 (32%)
		WW	266..295	CDD:395320	14/28 (50%)
		WW	335..364	CDD:395320	10/28 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4781
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.850