Protein Alignment kibra and Magi

DIOPT Version :9

• Sequence 1: NP_001034055.1
• Gene: kibra / 41783
• FlyBaseID: FBgn0262127
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_001286661.1
• Gene: Magi / 37403
• FlyBaseID: FBgn0034590
• Length: 1202
• Species: Drosophila melanogaster
• Alignment Length: 1026
• Identity: 201/1026 - (19%)
• Similarity: 347/1026 - (33%)
• Gaps: 312/1026 - (30%)

  Fly    40 QHTHHQQQQQHHSD-----FPLPDGWDIAKDFDGKTYYIDHINKKTTWLDPRDCYTKPQTFEDCV 99
            ||.:|:.    |.|     .|||..|:.|....|:.|:|||....:.|||||....:.::.|||.
  Fly   277 QHQNHES----HDDPGDGLGPLPPKWETAYTERGELYFIDHNTGTSHWLDPRLSKYQKKSLEDCC 337

  Fly   100 GDELPMGWEESYDPNIGPYYINHLAQSTQLEDPRQEWKTVQEQMLSDYLSAAQDQLENKREMFDV 164
            .||||.|||:..|...|.|:|:|:.:.||.|:|..|.|           ..|.:|.:.:::|...
  Fly   338 EDELPYGWEKIEDSMYGMYFIDHVNRRTQYENPVLEAK-----------RRAAEQSQQQQQMQQQ 391

  Fly   165 KQQRLLWAQEEYNHLKLAASRSSLCSSSSSMSRHDPE------------------------LLRA 205
            :||    .||:.:....|.|.:....::.:..:.:.|                        ||::
  Fly   392 QQQ----MQEQRSKTPTALSETMPTEAAEAHEQEEDESPMKLPYKFTRNPAELQGQRINTTLLKS 452

  Fly   206 DLML----------ARERVHQLKQELTHITNDISYTERGMNTLYSVGEKINARENGCYDIAEVHA 260
            ...|          |...|.:..|..|.:.|..::.:..:.|    |:.:....:.|. :...|
  Fly   453 SRGLGFTIVGSDGSAGGDVEEFLQIKTVVPNGPAWLDGQLQT----GDVLVYVNDTCV-LGYTH- 511

  Fly   261 IREEMLKVHKSLVSGEKVREELMR-------------SLVQIKNELGRQQISEENSDLASPFDRV 312
              .:|:.:.:|::.||:...|:.|             .:|......||:...:...::...::.:
  Fly   512 --HDMVNIFQSILPGERAALEVCRGYPLPFDPNDPNTEVVTTMAVDGRESDKQRRLNMDGNYNFL 574

  Fly   313 CVASQTDLCGSSGENLNG-GARFAEMAKTKWQYAEWRKHIKKLQQQLADHVERIEPGQLES---D 373
                  ||.|...:..:| |:.|..|.|.:.......|........:||..    .||:..   |
  Fly   575 ------DLSGEGAKKTSGSGSGFILMKKPEIYTFSIMKGSMGFGFTIADSA----CGQIVKKILD 629

  Fly   374 KDRILLIQEKEKLLNDLNSISLKSRSEEEKRVIHQTRHKLEEDLKEAYE---------------- 422
            ::....:.|.:.|| ::|.::::::          ....:.|.|||..:
  Fly   630 RNCCTQLMEGDVLL-EINGLNVRNK----------PHFYVVELLKECSQTTPTAVKIQRTPPDPP 683

  Fly   423 ANNTC-----VAN--RLR--------FHEE---KQLLLDKLQEAL---KSTKLLEERLKSFSSES 466
            ||||.     |.|  :||        |..:   ..|...:::|.|   ..|.|::.|......:|
  Fly   684 ANNTLAQLNQVGNVAKLRKNFVGSGLFRSKTPTADLYSTQVKEVLPMRPKTPLVDTRRSRVQIQS 748

  Fly   467 TFSISSGSSLGSLST-----------ASSKSALSFTDI-YIDPFAVDSPIDVVDLRRRSQRLFQQ 519
            ..:.......|:.:.           .|:.|.....|| |:||:.        .:.|.|:||
  Fly   749 PNNEVDDEGDGAAAAERKPLQLQTQGKSNSSLQELDDIPYMDPYP--------KISRLSERL--- 802

  Fly   520 HQQQRLHPVHPVLQQQQSAEVTLS----------PRSSLSMETPPA---SPMKYNAGADQTPQAL 571
                              |||||.          |.|...:..|.|   |...|:.      ||.
  Fly   803 ------------------AEVTLQGDANGGIYGMPPSMQPLPLPLAHHESCYCYDC------QAQ 843

  Fly   572 KEEPTYANALPAPPAYTAPPPVPISGVRARPYDLDSTVLDCMMLEAKLQKL----------NMGT 626
            :..|.|         :.......:||...:...|.:..|....::.::.:|          |:..
  Fly   844 RYRPGY---------FVQAQQAAMSGTTGQYSPLQTAHLQNERIQRRVNELLSDRRRVGFANLDP 899

  Fly   627 PLNLAVAP------LSPISEKPSLLDLPQEMLSRSSSTSNTRSVSAAVSNESVAGDSGVFEASR- 684
            |..:..:|      |..:||.....:|.:..|.|.:.....|.|            .|..|.|:
  Fly   900 PQQMQHSPSWRNGALLDVSEDADQCELTEVTLERQALGFGFRIV------------GGTEEGSQV 952

  Fly   685 --AHLPRKELA----QVQIGLKYLKQEGVLVVSLERANNLLALWTASADNSQVYLRAALLPNSLT 743
              .|:.....|    ::..|.:.|..:|:.|::... :.:::|...||...||.:       .|.
  Fly   953 TVGHIVPGGAADQDQRINTGDEILSIDGINVLNSSH-HKVVSLVGESALRGQVTM-------ILR 1009

  Fly   744 SIRTKALGDFQKPVFNDTFAVPITLDKLLTKSLQVTVVTMTGQKEEIIGTVQISMAEFNPEDSTL 808
            ..||..|.  |.||.......|..             |.::..:.|..|.|.||        |:.
  Fly  1010 RRRTPLLQ--QAPVSTQLRRYPYD-------------VIVSRHENEGFGFVIIS--------SSN 1051

  Fly   809 KWYNVLSSKFIP-----------------SFESLDIPSTSAAAAAAAVAAS-------------- 842
            .:|.....|.||                 :...::|...|.......:..|
  Fly  1052 HYYGSTIGKLIPGSPADRCGELKVGDRIVAVNRIEIAGMSHGDVVNLIKESGLHVRLTIGVPLKE 1116

  Fly   843 NAPNPGNNREESSDESTITSSQTSTLTRNQAPCMELQEQMAAELLGLGPLN 893
            ..|:||.:....|..:.:.:|  .:|.:.|   :..|:|:..:.|....||
  Fly  1117 GGPSPGGSSVGVSSNTPLQAS--PSLLKAQ---LSHQQQLPQQHLQQAQLN 1162

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kibra	NP_001034055.1	WW	57..87	CDD:238122	12/29 (41%)
		WW	103..132	CDD:278809	13/28 (46%)
		C2_Kibra	693..813	CDD:176062	26/123 (21%)
Magi	NP_001286661.1	WW	294..323	CDD:278809	11/28 (39%)
		WW	342..372	CDD:238122	13/29 (45%)
		PDZ	443..534	CDD:214570	17/98 (17%)
		DegQ	<455..534	CDD:223343	15/86 (17%)
		PDZ_signaling	606..668	CDD:238492	14/76 (18%)
		PDZ	925..1011	CDD:214570	20/105 (19%)
		PDZ_signaling	1029..1110	CDD:238492	15/101 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900