Protein Alignment kibra and Hecw2

DIOPT Version :9

• Sequence 1: NP_001034055.1
• Gene: kibra / 41783
• FlyBaseID: FBgn0262127
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_001101688.1
• Gene: Hecw2 / 316395
• RGDID: 1593244
• Length: 1578
• Species: Rattus norvegicus
• Alignment Length: 423
• Identity: 79/423 - (18%)
• Similarity: 140/423 - (33%)
• Gaps: 171/423 - (40%)

  Fly    33 HQQQQQQQHTHHQQQQQHHSD------------FPLPDGWDIAKDFDGKTYYIDHINKKTTWLDP 85
            |...:.::.|||.::.||:.|            ..||.||::..|..||.:::||.::.||::||
  Rat   958 HMITKVRRDTHHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDP 1022

  Fly    86 RDCYTKPQTFEDCVGDELPMGWEESYDPNIGPYYINHLAQSTQL------EDPRQEWKTVQEQML 144
            |                ||:   :|..|.....:..||.:....      ||.|.....|..:..
  Rat  1023 R----------------LPL---QSSRPTSALVHRQHLTRQRSHSAGEVGEDSRHAGPPVLPRPA 1068

  Fly   145 SDYLSAAQDQLENKREMFDVKQQRLLWAQEEYNHLKLAASRSSLCSSSSSMSRHDPELLRADLML 209
            |.:.:.::.|.:   :|..|          .||...:|..|             .|.:|
  Rat  1069 STFNTVSRPQYQ---DMVPV----------AYNDKIVAFLR-------------QPNIL------ 1101

  Fly   210 ARERVHQLKQELTHITNDISYTERGMNTLYSVGEKINARENGCYDIAEVHAIREEMLKVHKSLVS 274
                                             |.:..|:.   |:|..|::||::
  Rat  1102 ---------------------------------EILQERQP---DLARNHSLREKI--------- 1121

  Fly   275 GEKVREELMRSLVQIKNE--------LGRQQI------------SEENSDLASPFDRVCVASQTD 319
             :.:|.|....||::.::        |..::|            |...|...||.
  Rat  1122 -QFIRTEGTPGLVRLSSDADLVMLLSLFEEEIMSYVPPHALLHPSYCQSPRGSPV---------- 1175

  Fly   320 LCGSSGENLNGGARFAEMAKTKWQYAEWRKHIKKLQQQLADHVERIE-------PGQLESDKDRI 377
               ||.:|..|..|....|...::        :..:.:|.:...::|       ||:|:
  Rat  1176 ---SSPQNSPGTQRANARAPAPYK--------RDFEAKLRNFYRKLETKGYGQGPGKLK------ 1223

  Fly   378 LLIQEKEKLLND-LNSISLKSRSEEEKRVIHQT 409
             ||..::.||.| .|.|...||.:.::..::.|
  Rat  1224 -LIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVT 1255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kibra	NP_001034055.1	WW	57..87	CDD:238122	12/29 (41%)
		WW	103..132	CDD:278809	7/34 (21%)
		C2_Kibra	693..813	CDD:176062
Hecw2	NP_001101688.1	HECW_N	45..162	CDD:406866
		C2_NEDL1-like	185..321	CDD:176073
		MDN1	<396..741	CDD:227596
		NESP55	<464..632	CDD:115071
		WW	815..844	CDD:395320
		HECW1_helix	921..987	CDD:408233	7/28 (25%)
		WW	993..1024	CDD:197736	14/46 (30%)
		HECTc	1222..1576	CDD:238033	11/41 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900