DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kibra and Wwtr1

DIOPT Version :9

Sequence 1:	NP_001034055.1	Gene:	kibra / 41783	FlyBaseID:	FBgn0262127	Length:	1288	Species:	Drosophila melanogaster
Sequence 2:	NP_001020040.1	Gene:	Wwtr1 / 295062	RGDID:	1559609	Length:	395	Species:	Rattus norvegicus

Alignment Length:	257	Identity:	61/257 - (23%)
Similarity:	99/257 - (38%)	Gaps:	47/257 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 QQHTHHQQQQQHHSD-FPLPDGWDIAKDFDGKTYYIDHINKKTTWLDPRDCYTKP----QTFEDC 98
            |||.|.:||....:| .|||.||::.....|:.|:::||.|.|||.|||....:|    ......
  Rat   108 QQHAHLRQQSYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKVMNQPLNHVNLHPTI 172

  Fly    99 VGDELPMGWEESYDPNIGPYYINHLAQ---STQLEDPRQEWKTVQEQMLS--DYLSAAQDQLENK 158
            ....:|........||:.   :||..|   :|.|.......:.....::|  :.|:..|.|.:..
  Rat   173 TSTSVPQRSMAVSQPNLA---MNHQHQQVVATSLSPQNHPAQNPPTGLMSVPNALTTQQQQQQKL 234

  Fly   159 R-EMFDVKQQRLLWAQEEYNHLKLAASRSSLCSSSSSMSRHDPELLRADLMLARERVHQLKQELT 222
            | :...::::|:...|||     |....::||.          :|......:|......:..::.
  Rat   235 RLQRIQMERERIRMRQEE-----LMRQEAALCR----------QLPMETETMAPVNTPAMNTDMR 284

  Fly   223 HITNDIS--------YTERGMNTLYSVGEKINARENGCYDIAEVHAIREEMLKVHKSLVSGE 276
            .:||..|        |..|..:|...:|       .|||   .|....|:.|.....:.:||
  Rat   285 SVTNSSSDPFLNGGPYHSREQSTDSGLG-------LGCY---SVPTTPEDFLSNMDEMDTGE 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kibra	NP_001034055.1	WW	57..87	CDD:238122	13/29 (45%)
		WW	103..132	CDD:278809	8/31 (26%)
		C2_Kibra	693..813	CDD:176062
Wwtr1	NP_001020040.1	WW	125..156	CDD:197736	14/30 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900