Protein Alignment kibra and yap-1

DIOPT Version :10

• Sequence 1: NP_001034055.1
• Gene: kibra / 41783
• FlyBaseID: FBgn0262127
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_001369894.1
• Gene: yap-1 / 181267
• WormBaseID: WBGene00008748
• Length: 442
• Species: Caenorhabditis elegans
• Alignment Length: 291
• Identity: 65/291 - (22%)
• Similarity: 106/291 - (36%)
• Gaps: 76/291 - (26%)

  Fly     2 PNLQQTASQSQ-------------HHLH----------------PHHLRPQQQQQQHHHHHQQQQ 37
            |||..:.:..|             ||.|                |.|::....:..:.:....:.
 Worm   106 PNLHTSVNNGQSSATVPHPSHHNVHHQHSKSVSALPMTIGYSPVPSHVKSVSHEANYSYAGLSEI 170

  Fly    38 QQQHTHHQQQQ----------------QHHSDFPLPDGWDIAKDFDGKTYYIDHINKKTTWLDPR 86
            .||....||.:                |.....|:|.||::..|.||..|:.||.:|.|||.|||
 Worm   171 PQQQGMMQQNREKSLSLDPMRRPFMTPQDVEQLPMPQGWEMCYDSDGVRYFKDHNSKTTTWDDPR 235

  Fly    87 DCYTKPQTFEDCVGDELPMG-WEESYDPNIGPYYINHLAQSTQL--EDPRQEWKTVQEQMLSDYL 148
            ....:...|.  :|:.:... :...||.......:..:.|..|:  ..|:.::.: |:||  ||:
 Worm   236 LKQQEQTGFG--LGENIGQNRYNNCYDNGHSSRSLPSIHQHQQMIPNHPQPQYSS-QQQM--DYI 295

  Fly   149 SAAQDQLENKREMFDVKQQRLLWA------QEEYNHLKLAASRSSLCSSSSSMSRHDPELLRADL 207
                .||:|:|.|...|..:|:.:      |..|..:.        ..||:.|..|||..:....
 Worm   296 ----QQLQNERMMIQEKNAQLINSGLVDSPQPPYQAIS--------PMSSTMMHSHDPNFMYQQQ 348

  Fly   208 MLARERVHQLKQELTHITNDI--SYTERGMN 236
            ..|:   :..:|:..|..:.|  .|....||
 Worm   349 QQAQ---NSQQQQTPHTLHQIPNQYQNSQMN 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kibra	NP_001034055.1	WW	57..87	CDD:238122	15/29 (52%)
		WW	103..132	CDD:459800	4/31 (13%)
		C2_Kibra	693..813	CDD:176062
yap-1	NP_001369894.1	WW	206..236	CDD:238122	15/29 (52%)