Protein Alignment kibra and oxi-1

DIOPT Version :9

• Sequence 1: NP_001034055.1
• Gene: kibra / 41783
• FlyBaseID: FBgn0262127
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_499392.1
• Gene: oxi-1 / 176515
• WormBaseID: WBGene00003898
• Length: 1066
• Species: Caenorhabditis elegans
• Alignment Length: 838
• Identity: 151/838 - (18%)
• Similarity: 273/838 - (32%)
• Gaps: 306/838 - (36%)

  Fly   156 ENKREMFDVKQQRLLWAQEEYNHLKLAASRSSLCSSSSSMSRHDPELLRADLMLARERVH-QLKQ 219
            :|.||..:.:.||        ..::||             .:.:|.|:.   .|.|::.| ::|.
 Worm    10 KNAREREEEETQR--------RRIELA-------------HKLEPYLIG---YLTRKKFHGKIKT 50

  Fly   220 ELTHITNDISYTERGMNTLYSVGEKI--------NARENGCYDIAEVHAIREEMLKVHKSLVSGE 276
            ......||.:..|:...||..|.:.:        |:|||  .||..:..|...:      ::|.:
 Worm    51 FRPTFFNDFNDLEKSNKTLLPVAQMLVKVPRVIENSREN--KDIQMLCNICRHL------IISID 107

  Fly   277 KVREELMRSLVQIKNELGRQQISEENSDLASPFDRVCVASQTDLCGSSGENLNGGARFAEMAKTK 341
            ...:|:  |.|..  .|.:..|.|..|.:.|.|.::    ...||..:||      |.||:  .:
 Worm   108 SPSKEI--SFVAA--FLNKDTIKEATSLITSIFSQI----PQILCSINGE------RAAEL--KQ 156

  Fly   342 WQ-----------YAEWRKHIKKLQQQLADHVERI-------------EPGQLESDKDRILLIQE 382
            ||           .:.|      |..:.|..|:.:             ||...|.....:.:...
 Worm   157 WQCLIHFVIVFSSSSNW------LLVRNAPQVQTVLNGLCVKMMSLFYEPKGYEQMATSLFVSVN 215

  Fly   383 KEKLLNDLNSIS---------LKSRSEE----------------------------EKRVIHQTR 410
            ..|.|.::.:::         ||:.:.|                            ..::..:|.
 Worm   216 GHKPLINVETVNAQFSILCKPLKTENPELFSIFVLKVLTCPALLVHLNAQHVELLKTTKIFEKTL 280

  Fly   411 HKLEEDLKEAYEANNTCVANRLRFHEEKQLLLDKLQEALKSTKLLEERLKSFSSESTFSISSGSS 475
            |.|..:.:|.    .|.:..||..:    ||.:.:..|..:.|.||.:|..::.....|:|..:.
 Worm   281 HWLRANAEEI----ETGMDVRLLIN----LLANLVHFAYINDKTLESKLYEWTWAVGVSLSRCTE 337

  Fly   476 LGSLSTASSKSALSFTDIYIDPFAVDSPIDVVDLRRRSQR-----LFQQHQQQRLHPVH----PV 531
            | ::....:|::|.:.......:.:  |||     :|::.     |||.........|.    .:
 Worm   338 L-TVKHGGTKTSLHYWHPVFGHYLL--PID-----KRTEGALRNVLFQLKMLWSSRVVRCLFGNI 394

  Fly   532 LQQQQSAEVTLSPRSSLSMETPPASP---MKYNAGADQTPQALKEEPTYANALPAPPAYTAPPPV 593
            ::..::|..:::.....|.:...|..   .|.....|....:.|.|             :.|||.
 Worm   395 MENTKTASFSVTDGQKNSKDISAAFSKLWRKLGGSTDSASSSSKSE-------------SEPPPT 446

  Fly   594 PISGVRARPYDLDSTVLDCMM-------------------------------------------- 614
            .|: :..:.|   .|.|:.|:
 Worm   447 LIA-IVCQVY---MTALNTMVHMKGEIISGLCRDDQLLKQLWTYLREWGEKAGGTSGSIFNSSNA 507

  Fly   615 -----LEAKLQKLNM-GTP--------LNLAVAPLSPISEKPSLLDLPQEMLSRSSSTSNT---- 661
                 :.|.||.|.. .:|        ::.|.|.:|.:.|        :|:..:.:..||.
 Worm   508 EQWGPVSASLQSLKRPSSPHTATLRLFVDCAAAIISILDE--------EEIFEKETPFSNKELES 564

  Fly   662 ----------RSVSAAVSNESVAGDSGVFEASRAHLPRKELAQVQIGLKYLKQEGVLVVSLERAN 716
                      ||:.:...:|:.|..:|:|.:                     ...:|.|..||.:
 Worm   565 ICKYVNIFCFRSIWSGAVDETSANTTGLFHS---------------------MHSLLTVLYERDS 608

  Fly   717 NLLALWTASADNSQVYLRAALLPNSLTSIRTKALGDFQKPVFNDTFAVPITLDKLLTKSLQV--- 778
            ..    :.:|::|:.:|.:.:.|:|||....|..|.....:......|||. |::|....||
 Worm   609 RR----SFAANDSKFWLISEVKPSSLTIEYEKKSGKGVLMMRKMAHLVPIK-DRMLLFRRQVQDD 668

  Fly   779 --TVVT----------MTGQKEEIIGTVQISMAEFNPEDSTLKWYNVLSSKFIPSFES 824
              .|.|          :|.|:..||            ||.    :|.||...||:.:|
 Worm   669 KNRVATSLNDPQMQTWITVQRNRII------------EDG----FNHLSKLTIPALKS 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kibra	NP_001034055.1	WW	57..87	CDD:238122
		WW	103..132	CDD:278809
		C2_Kibra	693..813	CDD:176062	28/134 (21%)
oxi-1	NP_499392.1	HECTc	684..1064	CDD:238033	12/43 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900