Protein Alignment kibra and hecw-1

DIOPT Version :9

• Sequence 1: NP_001034055.1
• Gene: kibra / 41783
• FlyBaseID: FBgn0262127
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_001317872.1
• Gene: hecw-1 / 175438
• WormBaseID: WBGene00009738
• Length: 1247
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 98/545 - (17%)
• Similarity: 171/545 - (31%)
• Gaps: 202/545 - (37%)

  Fly    55 PLPDGWDIAKDFDGKTYYIDHINKKTTWLDPRDCYTKPQTFEDCVGDELPMGWEESYDPNIGPYY 119
            |||.||:.. ..:.:|.:::|.||:|::.|||  ..:.:|.....|..:|.....::...|....
 Worm   746 PLPSGWECI-TMNNRTVFLNHANKETSFYDPR--IRRFETKTSRRGRSVPSRSSTAHKGKIDHAL 807

  Fly   120 IN---HLAQSTQLEDPRQEWKTVQEQMLSDY--------------LSAAQDQLENKREMFDVKQQ 167
            |:   .|.:..|...|:...:..::.||.:.              ::.|...|::..|....:..
 Worm   808 ISKCEDLRKIAQDNFPQIAERISKKLMLIERFGGLAVASLANDLDITLALSMLDSNTEKLAGEGD 872

  Fly   168 RLLWAQEEYNHLKLAASRSSLCSSSSS----------MSRHDPELLRADLM-------------- 208
            .:....|:....||....|.||...|.          :...||.:|:...:
 Worm   873 NIKMFYEDMKKEKLGKGPSRLCWKVSRDRLLDDAFRIILNVDPFVLKKSRLHIRFEGELALDYGG 937

  Fly   209 LARERVHQLKQELTHITNDISYTERGMNTLYSVGEKINARENGC---------------YDIAEV 258
            |:||....|.:||.|..|  .|.|...|..:     :..|..||               ..:|.:
 Worm   938 LSREFFILLSRELFHPKN--GYFEYEGNDYH-----LQLRPRGCETEKEKKWLILCGRVLALAVI 995

  Fly   259 H--------------------------------------------AIREEMLKVHKSLVSGEKVR 279
            |                                            .:..||..|:.|:|:|:...
 Worm   996 HRCYIDVFFTNVFYKSLQKRPVTLMDFKESDAEFYKSMNWLLENDVVDLEMSFVYSSMVNGKLAE 1060

  Fly   280 EELMRSLVQIKNELGR-QQISEENSDLASPFDRVCVASQTDLCGSSGENLNGGARFAEMAKTKWQ 343
            :||:..        |. |.::|.|.  |...|.:|          ..:.:.|..:..|:..|.:.
 Worm  1061 QELVPG--------GESQMVTEANK--AEFIDLMC----------QKKAIRGVEKPLEILLTSFN 1105

  Fly   344 YAEWRKHIKKLQQQLADHVE-----RIEPGQLESDKDRILLIQEKEKLLNDLNSISLKSRSEEEK 403
                    :.|...|.:.:|     ||..|.||.|             |||..:.::......:.
 Worm  1106 --------QILNDNLLNSLESSDLKRILSGSLELD-------------LNDWRTNTIYKGGYSDC 1149

  Fly   404 RVI------------HQTRHKL--------------------EEDLKE----------AYEANNT 426
            .::            :|.|..|                    .|::.:          ::...:|
 Worm  1150 HIVVEWFWEVIETMTNQERFDLLLFVTGSSSVPFEGFSALRGNEEISKFCIEKWGDATSFPRAHT 1214

  Fly   427 CVANRLRF--HEEKQLLLDKLQEAL 449
            |. |||:.  :..||.|..|||:|:
 Worm  1215 CF-NRLQLPSYNTKQQLKSKLQQAI 1238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kibra	NP_001034055.1	WW	57..87	CDD:238122	10/29 (34%)
		WW	103..132	CDD:278809	5/31 (16%)
		C2_Kibra	693..813	CDD:176062
hecw-1	NP_001317872.1	FBA_2	230..285	CDD:311601
		WW	603..634	CDD:197736
		WW	746..777	CDD:197736	13/33 (39%)
		HECTc	918..1244	CDD:214523	63/370 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900