Protein Alignment kibra and Gas7

DIOPT Version :9

• Sequence 1: NP_001034055.1
• Gene: kibra / 41783
• FlyBaseID: FBgn0262127
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: XP_006532265.1
• Gene: Gas7 / 14457
• MGIID: 1202388
• Length: 476
• Species: Mus musculus
• Alignment Length: 549
• Identity: 101/549 - (18%)
• Similarity: 187/549 - (34%)
• Gaps: 186/549 - (33%)

  Fly    56 LPDG--WDIAKDFDG-----KTYYIDHINKKTTWLDPRDCYTKPQTFEDCVGDE-----LPMGWE 108
            :|||  |:..|| ||     ...|:..:.             ||.......|:|     ||.||.
Mouse    34 VPDGGWWEGEKD-DGLRGWFPASYVQLLE-------------KPGMVPPPPGEESQTVILPPGWH 84

  Fly   109 ESYDPNIGPYYINHLAQSTQLEDPRQEWKTVQEQMLSDYLSAAQDQLENKREMFDVKQQRLLWAQ 173
            ....|....||:|.....|..|.|..          |..:||:.
Mouse    85 SYLSPQGRRYYVNTTTNETTWERPSS----------SPGISASP--------------------- 118

  Fly   174 EEYNHLKLAASRSSLCSS-----SSSMSRHDPELLRADLMLARERVHQL---------------- 217
                    ...||||.::     :|....|.||.....|..:......|
Mouse   119 --------GPHRSSLPTTVNGYHASGTPAHPPETAHMSLRKSTGDSQNLGSSSPGRKQSKENTIT 175

  Fly   218 -------------KQELTHITNDISYTERGMNTLYSVGEKINARENGCYDIAEVHAIREEMLKVH 269
                         :|:|...| :.||.:      |...:|.:.:.||  .:|....:.::.||
Mouse   176 INCVTFPHPDTMPEQQLLKPT-EWSYCD------YFWADKKDPQGNG--TVAGFELLLQKQLK-- 229

  Fly   270 KSLVSGEKVREELMRSLVQIKNELGRQQISEENSDLASPFDRVCVASQTDLCGSSGE-------- 326
                 |:::::|:...:.:      |.:|.||.:...:...:..:|:|.:  ||.||
Mouse   230 -----GKQMQKEMSEFIRE------RIKIEEEYAKNLAKLSQNSLAAQEE--GSLGEAWAQVKKS 281

  Fly   327 -------NLNGGARF-AEMAKTKWQYAE-WRKHIKKLQQQLAD----------HVERIEPGQLES 372
                   :|...|:. :|:.|....:.| ::|.:||....:||          .||:......|.
Mouse   282 LADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTER 346

  Fly   373 DKDRILLIQEKEKLLNDLNSISLKSRSEEEKRVIHQTRHKLEEDLKEAYEANNTCVANRLRFHEE 437
            .||..:..|:.|        |.|.:::||:.:...:...:..:||....:..|..   :.::.||
Mouse   347 QKDLEMKTQQLE--------IKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQA---QSKWFEE 400

  Fly   438 ---KQLLLDKLQEALKSTKLLEERLKSFSSESTFSISSGSSLGSLSTASSKSALSFTDIYIDPFA 499
               ..|.|::|:  ::..:::.:.|..::     .:...:.:.:.||             ::|
Mouse   401 MVTTTLELERLE--VERVEMIRQHLCQYT-----QLRHETDMFNQST-------------VEP-- 443

  Fly   500 VDSPIDVVDLRRRSQRLFQQHQQQRLHPV 528
            ||..:..||..:..:...::|:...:.||
Mouse   444 VDQLLRKVDPAKDRELWVREHKTGNIRPV 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kibra	NP_001034055.1	WW	57..87	CDD:238122	9/36 (25%)
		WW	103..132	CDD:278809	10/28 (36%)
		C2_Kibra	693..813	CDD:176062
Gas7	XP_006532265.1	SH3_GAS7	5..57	CDD:212763	8/23 (35%)
		WW_FCH_linker	109..201	CDD:374680	17/131 (13%)
		F-BAR_GAS7	214..446	CDD:153333	51/281 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900