DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BigH1 and h1m

DIOPT Version :9

Sequence 1:	NP_650383.2	Gene:	BigH1 / 41780	FlyBaseID:	FBgn0038252	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	XP_005174537.2	Gene:	h1m / 327403	ZFINID:	ZDB-GENE-030131-5614	Length:	290	Species:	Danio rerio

Alignment Length:	241	Identity:	70/241 - (29%)
Similarity:	93/241 - (38%)	Gaps:	26/241 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 PDSDNPKSMVPK--PKGTLISLALMAIGKLASRSGSSVQAIMTYLKDNGQEWKDPKKTARLLHRA 148
            |:..|.||...|  |..:.:.:...|:.:|.||.|.|.|||..|:|:. ....|..:...::.||
Zfish    63 PEDSNAKSAARKVSPHPSTMEMVKEALKELDSRKGVSAQAIRGYIKEK-YTTVDETRLKYMVRRA 126

  Fly   149 LKLAEANGEVVMVKRSFKLTDKQKNSSKAVEKMKAKKQKEKEKKAKVEKVLKEKIQKKEAKA-KM 212
            |......|..|....|...|..|.....|.      |.|.||.||:    .||.....|.|| |.
Zfish   127 LNKGMDTGVFVRPANSGSTTGAQGRFRIAA------KTKAKEAKAQ----SKENADPNEPKATKP 181

  Fly   213 KEKKASKEKSSKPTERKTKQAVKKKKPEDGTKDNPPASKAASSAAAQAMLETSQTAIPEAGKKPA 277
            |:.||:|.|....|:.|   ..|||:..|..|.........:|..|.|....::.|..|.|.||.
Zfish   182 KKAKATKAKGEGATKEK---PTKKKETTDDAKPKTSEQNGTASKVAPAKKPKAKNAAGEGGAKPK 243

  Fly   278 KTKVKLQADSSEAGKTKKSRK---------SIGTLAQPKAARPKVK 314
            .:|.|...:.:|....||..|         ..|..|..||...:.|
Zfish   244 PSKAKASKEGAEEPAAKKGGKKNAVKAEDGESGAAATEKAPGKRAK 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BigH1	NP_650383.2	H15	109..167	CDD:294056	18/57 (32%)
h1m	XP_005174537.2	Linker_histone	78..154	CDD:306920	20/76 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11467
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100