Protein Alignment CG3505 and TMPRSS11D

DIOPT Version :10

• Sequence 1: NP_650380.2
• Gene: CG3505 / 41777
• FlyBaseID: FBgn0038250
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_004253.1
• Gene: TMPRSS11D / 9407
• HGNCID: 24059
• Length: 418
• Species: Homo sapiens
• Alignment Length: 340
• Identity: 90/340 - (26%)
• Similarity: 127/340 - (37%)
• Gaps: 113/340 - (33%)

  Fly    55 SGNL------------SQSDRNLLRDNQCGVRGNDVQVCCPSTAGLGALTHPLLPSDCGKVRWQR 107
            ||||            .|:..|.| .|:||             ||...:|          :..||
Human   146 SGNLEINPSTEITSLTDQAAANWL-INECG-------------AGPDLIT----------LSEQR 186

  Fly   108 -SNDTDTRIREFPWLALIEYTRGNQEKIHACGGVLISDRYVLTAAHCVAQ-------AATSNLQI 164
             ...|:.....:||...:.....     |.|||.||::.::||||||...       .|||.:..
Human   187 ILGGTEAEEGSWPWQVSLRLNNA-----HHCGGSLINNMWILTAAHCFRSNSNPRDWIATSGIST 246

  Fly   165 TAVRLGEWDTSTNPDCQYHEDSKVADCAPPYQDIAIEELLPHPLYNRTDRTQINDIALVRLASPA 229
            |..:|                           .:.:..:|.|..|.  ..|..||||||||.:..
Human   247 TFPKL---------------------------RMRVRNILIHNNYK--SATHENDIALVRLENSV 282

  Fly   230 KLNDFVQPICLPNKQLRADELEDLVTE---------VAGWQAS-----SSQRMRKGYVTISSIEE 280
            .....:..:|||           ..|:         |.||.|.     :...:|:|.|.|.|.:.
Human   283 TFTKDIHSVCLP-----------AATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDV 336

  Fly   281 CQRKYASQQLRIQASKLC-GLTNS--QECYGNAGGPLMLFKNDG---YLLGGLVSFGPVPCPNPD 339
            |...: |....|.:..|| |:...  ..|.|::||||:  :.|.   :.:.|:||:|. .|..||
Human   337 CNAPH-SYNGAILSGMLCAGVPQGGVDACQGDSGGPLV--QEDSRRLWFIVGIVSWGD-QCGLPD 397

  Fly   340 WPDVYTRVASYIDWI 354
            .|.|||||.:|:|||
Human   398 KPGVYTRVTAYLDWI 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3505	NP_650380.2	CLIP	32..82	CDD:463440	10/38 (26%)
		Tryp_SPc	111..356	CDD:238113	75/271 (28%)
TMPRSS11D	NP_004253.1	SEA	48..146	CDD:460188	90/340 (26%)
		Tryp_SPc	187..415	CDD:238113	75/275 (27%)