Protein Alignment CG3505 and TMPRSS5

DIOPT Version :10

• Sequence 1: NP_650380.2
• Gene: CG3505 / 41777
• FlyBaseID: FBgn0038250
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_110397.2
• Gene: TMPRSS5 / 80975
• HGNCID: 14908
• Length: 457
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 82/314 - (26%)
• Similarity: 127/314 - (40%)
• Gaps: 88/314 - (28%)

  Fly    66 LRDNQCGVRGNDVQVCCPSTAGLGALTHPLLPSDCGKVRWQRSNDTDTRIREFPWLALIEYTRGN 130
            ||.::||.|....::....:...|              ||             ||.|.:  ..|.
Human   204 LRCSECGARPLASRIVGGQSVAPG--------------RW-------------PWQASV--ALGF 239

  Fly   131 QEKIHACGGVLISDRYVLTAAHCVAQAATSNLQITAVRLGEWDTSTNPDCQYHEDSKVADCAPPY 195
            :   |.|||.:::.|:|:|||||:.       .....||..|        :.|..........|:
Human   240 R---HTCGGSVLAPRWVVTAAHCMH-------SFRLARLSSW--------RVHAGLVSHSAVRPH 286

  Fly   196 QDIAIEELLPHPLYNRTDRTQINDIALVRLASPAKLNDFVQPICLPNKQ---------------- 244
            |...:|.::|||||:..:...  |:||:||.:....:|.|..:|||.|:
Human   287 QGALVERIIPHPLYSAQNHDY--DVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGH 349

  Fly   245 ------LRADELEDLVTEVAGWQASSSQRMRKGYVTISSIEECQRKYASQQLRIQASKLCGLTNS 303
                  ..:|.|:|.|..:...|..:|..:..|.:|...:  |            |..|.|  .:
Human   350 THPSHTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTPRML--C------------AGYLDG--RA 398

  Fly   304 QECYGNAGGPLMLFKNDGYLLGGLVSFGPVPCPNPDWPDVYTRVASYIDWIHDS 357
            ..|.|::||||:....|.:.|.|:||:|. .|..|:.|.||.:||.::|||||:
Human   399 DACQGDSGGPLVCPDGDTWRLVGVVSWGR-GCAEPNHPGVYAKVAEFLDWIHDT 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3505	NP_650380.2	CLIP	32..82	CDD:463440	5/15 (33%)
		Tryp_SPc	111..356	CDD:238113	72/266 (27%)
TMPRSS5	NP_110397.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		SRCR_2	116..213	CDD:464747	4/8 (50%)
		Tryp_SPc	217..448	CDD:214473	73/296 (25%)