Protein Alignment CG3505 and KLK10

DIOPT Version :10

• Sequence 1: NP_650380.2
• Gene: CG3505 / 41777
• FlyBaseID: FBgn0038250
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_002767.2
• Gene: KLK10 / 5655
• HGNCID: 6358
• Length: 276
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 79/299 - (26%)
• Similarity: 130/299 - (43%)
• Gaps: 73/299 - (24%)

  Fly    86 AGLGALTHPLLPSDCGKVRWQRSNDTDTRI-----------REFPWLALIEYTRGNQEKIHACGG 139
            |.|.|....|||.:            |||:           ...||    :.:..|....| |.|
Human    26 AQLWAAEAALLPQN------------DTRLDPEAYGSPCARGSQPW----QVSLFNGLSFH-CAG 73

  Fly   140 VLISDRYVLTAAHC-----VAQAATSNLQITAVRLGEWDTSTNPDCQYHEDSKVADCAPPYQDIA 199
            ||:...:|||||||     .|:....:|.:.........|.:....:||:.|     .|
Human    74 VLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPKYHQGS-----GP------ 127

  Fly   200 IEELLPHPLYNRTDRTQINDIALVRLASPAKLNDFVQPICLPNKQLRADELEDLVTEVAGWQASS 264
               :||.       ||..:|:.|::||.|..|...|:.:.||.:..:..:    ..:||||..::
Human   128 ---ILPR-------RTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD----QCQVAGWGTTA 178

  Fly   265 SQRMR--KGY----VTISSIEECQRKYASQQLRIQASKLC-GLTNSQE-CYGNAGGPLMLFKNDG 321
            ::|::  ||.    :||.|.:||:..|...   :..:.:| ||...|: |..::||||:..:.
Human   179 ARRVKYNKGLTCSSITILSPKECEVFYPGV---VTNNMICAGLDRGQDPCQSDSGGPLVCDET-- 238

  Fly   322 YLLGGLVSFGPVPCPNPDWPDVYTRVASYIDWIHDSLKA 360
              |.|::|:|..||.:...|.|||::..|:.||:..:::
Human   239 --LQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRS 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3505	NP_650380.2	CLIP	32..82	CDD:463440
		Tryp_SPc	111..356	CDD:238113	73/268 (27%)
KLK10	NP_002767.2	Tryp_SPc	49..272	CDD:238113	70/259 (27%)