Protein Alignment CG3505 and ACR

DIOPT Version :10

• Sequence 1: NP_650380.2
• Gene: CG3505 / 41777
• FlyBaseID: FBgn0038250
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 77/280 - (27%)
• Similarity: 124/280 - (44%)
• Gaps: 48/280 - (17%)

  Fly   100 CGKVRWQRSNDTDTRI--------REFPWLALIEYTRGNQEKIHACGGVLISDRYVLTAAHCVAQ 156
            || :|::::.....||        ..:||:..::....|..:.|.|||.|::.|:|||||||.
Human    29 CG-LRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCF-- 90

  Fly   157 AATSNLQITAVRLGEWDTSTNPDCQYHEDSKVADCAPPYQDIAIEELLPHPLYNRTDRTQINDIA 221
            ...:|:....:..|.      .:..|..:..|   ..|.|:..:|:::.|..||  ..|:.||||
Human    91 VGKNNVHDWRLVFGA------KEITYGNNKPV---KAPLQERYVEKIIIHEKYN--SATEGNDIA 144

  Fly   222 LVRLASPAKLNDFVQPICLPNKQL---RADELEDLVTEVAGW------QASSSQRMRKGYVTISS 277
            ||.:..|.....|:.|.|||:.:.   |..:    ...||||      ....|..:.:..|.:..
Human   145 LVEITPPISCGRFIGPGCLPHFKAGLPRGSQ----SCWVAGWGYIEEKAPRPSSILMEARVDLID 205

  Fly   278 IEECQRKYASQQL---RIQASKLCG---LTNSQECYGNAGGPLML--FKNDGYLLGGLVSFGPVP 334
            ::.|.    |.|.   |:|.:.:|.   :.....|.|::|||||.  .|...|::.|:.|:| |.
Human   206 LDLCN----STQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWG-VG 265

  Fly   335 CPNPDWPDVYTRVASYIDWI 354
            |.....|.:||....|::||
Human   266 CARAKRPGIYTATWPYLNWI 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3505	NP_650380.2	CLIP	32..82	CDD:463440
		Tryp_SPc	111..356	CDD:238113	74/269 (28%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	72/264 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421