DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3505 and CG5255

DIOPT Version :9

Sequence 1:	NP_650380.2	Gene:	CG3505 / 41777	FlyBaseID:	FBgn0038250	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_650604.1	Gene:	CG5255 / 42073	FlyBaseID:	FBgn0038485	Length:	273	Species:	Drosophila melanogaster

Alignment Length:	239	Identity:	64/239 - (26%)
Similarity:	104/239 - (43%)	Gaps:	55/239 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 HACGGVLISDRYVLTAAHCVAQAATSNLQITAVRL--GEWDTSTNPDCQYHEDSKVADCAPPYQD 197
            |:|||.:|.:|:::|||||     |...|.||.|:  |..|...|....|:.|
  Fly    55 HSCGGAIIDERWIITAAHC-----TRGRQATAFRVLTGTQDLHQNGSKYYYPD------------ 102

  Fly   198 IAIEELLPHPLYNRTDRTQINDIALVRLASPAKLNDFVQPI------CLPNKQLRADELEDLVTE 256
                .::.|.  |...|...|||||:.|......::..||:      .:|..:|       |:|
  Fly   103 ----RIVEHS--NYAPRKYRNDIALLHLNESIVFDNATQPVELDHEALVPGSRL-------LLT- 153

  Fly   257 VAGWQASS-----SQRMRKGYVTISSIEECQRKYASQQLRIQASKLCGLTNSQE--CYGNAGGPL 314
              ||...|     ..|::...|.....|:|:..: ....|:....:|...:...  |:|::||||
  Fly   154 --GWGTLSLGGDVPARLQSLEVNYVPFEQCRAAH-DNSTRVDIGHVCTFNDKGRGACHGDSGGPL 215

  Fly   315 MLFKNDGYLLGGLVSFGPVPCPNPDWPDVYTRVASYIDWIHDSL 358
            :   ::|.|: .||::| :||.. .:||.:..::.|.|:|...|
  Fly   216 V---HNGKLV-ALVNWG-LPCAK-GYPDAHASISYYHDFIRTHL 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3505	NP_650380.2	CLIP	30..82	CDD:288855
		Tryp_SPc	111..356	CDD:238113	63/235 (27%)
		Tryp_SPc	111..354	CDD:214473	62/233 (27%)
CG5255	NP_650604.1	Tryp_SPc	29..249	CDD:214473	62/233 (27%)
CG5255	NP_650604.1	Tryp_SPc	30..252	CDD:238113	63/236 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437246
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030