DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3505 and modSP

DIOPT Version :9

Sequence 1:	NP_650380.2	Gene:	CG3505 / 41777	FlyBaseID:	FBgn0038250	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster

Alignment Length:	339	Identity:	81/339 - (23%)
Similarity:	128/339 - (37%)	Gaps:	92/339 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 GNDVQVCCPSTAGLGALTHPLLP------------------SDCGKVRWQRSNDTDTRIREF--- 118
            |.:|:..|.:    |..|...||                  .|||::.        |.|::|
  Fly   319 GTEVKFVCST----GFKTLSPLPEMRCMKGGYWNRGRQRCEQDCGQLA--------TPIKQFSSG 371

  Fly   119 ---------PWLALIEYTRGNQEKIH-ACGGVLISDRYVLTAAHCVAQAAT------SNLQITAV 167
                     ||...: |...|::..| .|||.|::...|:||||||....|      ...::.|.
  Fly   372 GYTINNTVVPWHVGL-YVWHNEKDYHFQCGGSLLTPDLVITAAHCVYDEGTRLPYSYDTFRVIAA 435

  Fly   168 RLGEWDTSTNPDCQYHEDSKVADCAPPYQDIAIEELLPHPLYNRTDRTQINDIALVRLASPAKLN 232
            :.......|.|: :...|.::.:.||.|:             .||: ....|:||:.|..|.:|:
  Fly   436 KFYRNYGETTPE-EKRRDVRLIEIAPGYK-------------GRTE-NYYQDLALLTLDEPFELS 485

  Fly   233 DFVQPICLPNKQLRADE--LEDLVTEVAGWQASSSQRMRKGYVTISSIEECQRKYASQQLR-IQA 294
            ..::|||:........|  .:|:..:.|||...:...::.......|...|:|     .|| |||
  Fly   486 HVIRPICVTFASFAEKESVTDDVQGKFAGWNIENKHELQFVPAVSKSNSVCRR-----NLRDIQA 545

  Fly   295 SKLCGLT--NSQECYGNAGG------PLMLF---KNDGYLLGGLVSFGPVPCPNPDW----PDVY 344
            .|.|..|  .|..|.|::||      |...|   ....:.|.|::|    ..||.|.    ..|.
  Fly   546 DKFCIFTQGKSLACQGDSGGGFTSELPTNAFSTWNTARHFLFGVIS----NAPNADQCAHSLTVM 606

  Fly   345 TRVASYIDWIHDSL 358
            |.:..:.|.|.:::
  Fly   607 TNIQHFEDMILNAM 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3505	NP_650380.2	CLIP	30..82	CDD:288855	2/6 (33%)
		Tryp_SPc	111..356	CDD:238113	71/281 (25%)
		Tryp_SPc	111..354	CDD:214473	70/279 (25%)
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512	7/38 (18%)
		Tryp_SPc	371..616	CDD:214473	67/269 (25%)
		Tryp_SPc	371..591	CDD:304450	60/240 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437243
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030