Protein Alignment CG3505 and TMPRSS11F

DIOPT Version :10

• Sequence 1: NP_650380.2
• Gene: CG3505 / 41777
• FlyBaseID: FBgn0038250
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_997290.2
• Gene: TMPRSS11F / 389208
• HGNCID: 29994
• Length: 438
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 87/304 - (28%)
• Similarity: 133/304 - (43%)
• Gaps: 54/304 - (17%)

  Fly    59 SQSDRNLLRDNQCGVRGNDVQVCCPSTAGLGALTHPLLPSDCGKVRWQRSNDTDTRIREFPWLAL 123
            |:..|||| :::||:|             :.:...| ||:.....|..:..:|... .|:||.|.
Human   175 SKKMRNLL-NSRCGIR-------------MTSSNMP-LPASSSTQRIVQGRETAME-GEWPWQAS 223

  Fly   124 IEYTRGNQEKIHACGGVLISDRYVLTAAHCVAQAATSNLQITAVRLGEWDTSTNPDCQYHEDSKV 188
            ::.....    |.||..|||:.::||||||.                 |   .|.|......:..
Human   224 LQLIGSG----HQCGASLISNTWLLTAAHCF-----------------W---KNKDPTQWIATFG 264

  Fly   189 ADCAPPYQDIAIEELLPHPLYNRTDRTQINDIALVRLASPAKLNDFVQPICLPNKQLRADELEDL 253
            |...||.....:.:::.|..|:|  .|..||||||:|::..:.::.||.:|||:..::......:
Human   265 ATITPPAVKRNVRKIILHENYHR--ETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSV 327

  Fly   254 VTEVAGW-----QASSSQRMRKGYVTISSIEECQRKYASQQLRIQASKLC-GLTNSQ--ECYGNA 310
            .  |.|:     .......:|:..|...|.:.|.||.....| |....|| |....:  .|.|::
Human   328 F--VTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGL-ITPGMLCAGFMEGKIDACKGDS 389

  Fly   311 GGPLMLFKNDGYLLGGLVSFGPVPCPNPDWPDVYTRVASYIDWI 354
            ||||:...:|.:.:.|:||:|. .|..|..|.|||||..|.|||
Human   390 GGPLVYDNHDIWYIVGIVSWGQ-SCALPKKPGVYTRVTKYRDWI 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3505	NP_650380.2	CLIP	32..82	CDD:463440	8/22 (36%)
		Tryp_SPc	111..356	CDD:238113	75/252 (30%)
TMPRSS11F	NP_997290.2	SEA	59..158	CDD:460188
		Tryp_SPc	206..435	CDD:238113	75/258 (29%)