DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3505 and CG6592

DIOPT Version :9

Sequence 1:	NP_650380.2	Gene:	CG3505 / 41777	FlyBaseID:	FBgn0038250	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_648016.1	Gene:	CG6592 / 38687	FlyBaseID:	FBgn0035669	Length:	438	Species:	Drosophila melanogaster

Alignment Length:	256	Identity:	72/256 - (28%)
Similarity:	114/256 - (44%)	Gaps:	47/256 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 FPWLA--LIEYTRGNQEKIHACGGVLISDRYVLTAAHCVAQAATSNLQITAVRLGEWDTSTNPDC 180
            ||:..  |::..:|    ::.|||.||||::|:||||||..|..:     .|.||     .|...
  Fly   134 FPYQVGMLLQRPKG----LYWCGGSLISDKHVITAAHCVDMAKRA-----LVFLG-----ANEIK 184

  Fly   181 QYHEDSKVADCAPPYQDIAIEELLPHPLYNRTDRTQINDIALVRLASPAKLNDFVQPICLPNKQL 245
            ...|..:|....|.      |....:|.:|  .:...:|||:|||......|:.:.||.||.:..
  Fly   185 NAKEKGQVRLMVPS------ENFQIYPTWN--PKRLKDDIAIVRLPHAVSFNERIHPIQLPKRHY 241

  Fly   246 RADELEDLVTEVAGWQASSSQRMRKGYVTISSI-----------EECQRKYASQQLRIQASKLC- 298
            .....::.:...:||     .|...|...||::           ..|:..:   .|..:.:.:|
  Fly   242 EYRSFKNKLAIASGW-----GRYATGVHAISNVLRYVQLQIIDGRTCKSNF---PLSYRGTNICT 298

  Fly   299 -GLTNSQECYGNAGGPLMLFKNDG--YLLGGLVSFGPVPCPNPDWPDVYTRVASYIDWIHD 356
             |......|.|::||||:|.:...  .:|.|:.|||.:...:..:|..:|:||||:|||.|
  Fly   299 SGRNARSTCNGDSGGPLVLQRRHSKKRVLVGITSFGSIYGCDRGYPAAFTKVASYLDWISD 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3505	NP_650380.2	CLIP	30..82	CDD:288855
		Tryp_SPc	111..356	CDD:238113	71/254 (28%)
		Tryp_SPc	111..354	CDD:214473	69/252 (27%)
CG6592	NP_648016.1	Tryp_SPc	122..357	CDD:214473	69/252 (27%)
CG6592	NP_648016.1	Tryp_SPc	123..359	CDD:238113	71/254 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436422
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940