Protein Alignment CG3505 and KLK13

DIOPT Version :10

• Sequence 1: NP_650380.2
• Gene: CG3505 / 41777
• FlyBaseID: FBgn0038250
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_056411.1
• Gene: KLK13 / 26085
• HGNCID: 6361
• Length: 277
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 90/326 - (27%)
• Similarity: 138/326 - (42%)
• Gaps: 89/326 - (27%)

  Fly    50 MRILLSGNLSQSDRNLLRDNQCGVRGNDVQVCCPSTAGLGALTHPLLPSDCGKVRWQRSNDTDTR 114
            :.:.|||.:||....:|..|              .|:|       .||.  |...:..|.
Human    11 LTLALSGGVSQESSKVLNTN--------------GTSG-------FLPG--GYTCFPHSQ----- 47

  Fly   115 IREFPWLALIEYTRGNQEKIHACGGVLISDRYVLTAAHCVAQAATSNL---QITAVRLGEWDTST 176
                ||.|.: ..:|..    .|||||:..::|||||||:.:.....|   .:..|..||
Human    48 ----PWQAAL-LVQGRL----LCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGE----- 98

  Fly   177 NPDCQYHEDSKVADCAPPYQDIAIEELLPHPLYNRTDRTQIN---DIALVRLASPAKLNDFVQPI 238
                |..|               :...:|||.|.|:. |.:|   ||.|:.|.||.:|..::|.:
Human    99 ----QVRE---------------VVHSIPHPEYRRSP-THLNHDHDIMLLELQSPVQLTGYIQTL 143

  Fly   239 CLP-NKQLRADELEDLVTEVAGWQASSS------QRMRKGYVTISSIEECQRKYASQQLRIQASK 296
            .|. |.:|    .......|:||..::|      :.::...:.:.|.|||::.|..   :|..:.
Human   144 PLSHNNRL----TPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPG---KITDNM 201

  Fly   297 LCGLT---NSQECYGNAGGPLMLFKNDGYLLGGLVSFGPVPCPNPDWPDVYTRVASYIDWIHDSL 358
            ||..|   ....|.|::||||:..:.    |.|:||:|..||..||.|.|||||:.|:.||.:::
Human   202 LCAGTKEGGKDSCEGDSGGPLVCNRT----LYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262

  Fly   359 K 359
            :
Human   263 R 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3505	NP_650380.2	CLIP	32..82	CDD:463440	7/31 (23%)
		Tryp_SPc	111..356	CDD:238113	77/260 (30%)
KLK13	NP_056411.1	Tryp_SPc	38..261	CDD:238113	79/274 (29%)