Protein Alignment CG3505 and KLK5

DIOPT Version :10

• Sequence 1: NP_650380.2
• Gene: CG3505 / 41777
• FlyBaseID: FBgn0038250
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 82/320 - (25%)
• Similarity: 128/320 - (40%)
• Gaps: 94/320 - (29%)

  Fly    76 NDVQVCCPSTA-------GLGALTHPLLPSDCGKVRWQRSNDTDTRI--------REFPWLALIE 125
            |||....||..       .|||          |.....||:|:.:||        ...||.|.:
Human    31 NDVSCDHPSNTVPSGSNQDLGA----------GAGEDARSDDSSSRIINGSDCDMHTQPWQAAL- 84

  Fly   126 YTRGNQEKIHACGGVLISDRYVLTAAHCVAQAATSNLQITAVRLGEWDTSTNPDCQYHEDSKVAD 190
            ..|.||   ..||.||:..:::||||||       ..::..||||.:..|.    .|....::
Human    85 LLRPNQ---LYCGAVLVHPQWLLTAAHC-------RKKVFRVRLGHYSLSP----VYESGQQM-- 133

  Fly   191 CAPPYQDIAIEELLPHPLYNRTDRTQINDIALVRLASPAKLNDFVQPI------------CLPNK 243
                :|.:   :.:|||.|:....:  ||:.|::|....:....|:||            ||
Human   134 ----FQGV---KSIPHPGYSHPGHS--NDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCL--- 186

  Fly   244 QLRADELEDLVTEVAGWQASSSQRMRKGYV------TISSIEECQRKYASQQLRIQASKLCG--L 300
                         |:||..:.|.::....|      ::.|.:.|:..|..|   |..:..|.  .
Human   187 -------------VSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQ---IDDTMFCAGDK 235

  Fly   301 TNSQECYGNAGGPLMLFKNDGYLLGGLVSFGPVPCPNPDWPDVYTRVASYIDWIHDSLKA 360
            .....|.|::|||::...:    |.||||:|..||..|:.|.|||.:..:..||.::::|
Human   236 AGRDSCQGDSGGPVVCNGS----LQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQA 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3505	NP_650380.2	CLIP	32..82	CDD:463440	3/5 (60%)
		Tryp_SPc	111..356	CDD:238113	69/272 (25%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		10/40 (25%)
		Tryp_SPc	66..285	CDD:214473	67/267 (25%)