Protein Alignment CG3505 and Tmprss3

DIOPT Version :10

• Sequence 1: NP_650380.2
• Gene: CG3505 / 41777
• FlyBaseID: FBgn0038250
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: NP_001157248.1
• Gene: Tmprss3 / 140765
• MGIID: 2155445
• Length: 475
• Species: Mus musculus
• Alignment Length: 447
• Identity: 102/447 - (22%)
• Similarity: 175/447 - (39%)
• Gaps: 138/447 - (30%)

  Fly     4 FPALLVVVG------SLALGANAQLP---PINCVAKIPSGRVTGHCISIREC----DYFMRILLS 55
            ||  ::|:|      :||:|......   ...|.:......:|..|..:.:|    |.:..:.:|
Mouse    71 FP--IIVIGIIALILALAIGLGIHFDCSGKYRCHSSFKCIELTARCDGVSDCKNAEDEYRCVRVS 133

  Fly    56 GN-------LSQSDRNLLRDNQCGVRGNDVQVCCPSTAGLG------------------------ 89
            |.       .:.:.|.:..|:.   :.:..::.|   |.||
Mouse   134 GQRAALQVFTAAAWRTMCSDDW---KSHYAKIAC---AQLGFPSYVSSDHLRVDALEEQFQGDFV 192

  Fly    90 ALTHPLLPSD--------------C--GKVRWQRSNDTDTR--------------IREFPWLALI 124
            ::.| ||..|              |  |.|...:.:...||              :.::||...:
Mouse   193 SINH-LLSDDKVTALHHSVYMREGCTSGHVVTLKCSACGTRTGYSPRIVGGNMSSLTQWPWQVSL 256

  Fly   125 EYTRGNQEKIHACGGVLISDRYVLTAAHCVAQAATSNLQITAVRLGEWDTSTNPDCQYHEDS--- 186
            ::     :..|.|||.:|:..:::||||||                 :|.       ||..|
Mouse   257 QF-----QGYHLCGGSIITPLWIVTAAHCV-----------------YDL-------YHPKSWTV 292

  Fly   187 ---KVADCAPPYQDIAIEELLPHPLYNRTDRTQINDIALVRLASPAKLNDFVQPICLPNKQLRAD 248
               .|:....|.....:|:::.|..|.  .:...|||||::|:.|...::.:|||||||.:   :
Mouse   293 QVGLVSLMDSPVPSHLVEKIIYHSKYK--PKRLGNDIALMKLSEPLTFDETIQPICLPNSE---E 352

  Fly   249 ELED-LVTEVAGWQAS-----SSQRMRKGYVTISSIEECQRKYASQQLRIQASKLC-----GLTN 302
            ...| .:...:||.|:     :|..:....|.:.|.:.|..:.....: |..|.||     |..:
Mouse   353 NFPDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGI-ISPSMLCAGYLKGGVD 416

  Fly   303 SQECYGNAGGPLMLFKNDGYLLGGLVSFGPVPCPNPDWPDVYTRVASYIDWIHDSLK 359
            |  |.|::||||:..:...:.|.|..||| :.|...:.|.||||:.|::||||:.|:
Mouse   417 S--CQGDSGGPLVCQERRLWKLVGATSFG-IGCAEVNKPGVYTRITSFLDWIHEQLE 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3505	NP_650380.2	CLIP	32..82	CDD:463440	8/60 (13%)
		Tryp_SPc	111..356	CDD:238113	73/275 (27%)
Tmprss3	NP_001157248.1	LDLa	96..129	CDD:238060	5/32 (16%)
		SRCR_2	134..233	CDD:464747	15/105 (14%)
		Tryp_SPc	239..468	CDD:238113	72/266 (27%)