DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3505 and CG43110

DIOPT Version :9

Sequence 1:	NP_650380.2	Gene:	CG3505 / 41777	FlyBaseID:	FBgn0038250	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001246396.1	Gene:	CG43110 / 12798330	FlyBaseID:	FBgn0262570	Length:	483	Species:	Drosophila melanogaster

Alignment Length:	251	Identity:	65/251 - (25%)
Similarity:	108/251 - (43%)	Gaps:	53/251 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 EYTRGNQEKIH-ACGGVLISDRYVLTAAHCVAQAATSNLQITAVRLGEWDTSTNPDCQYHEDSKV 188
            :|..|.....| .|||.:|.:.:|||.|||      .:.|...||||.::.:       |
  Fly    48 QYMAGIFNTTHLLCGGTIIHEDFVLTVAHC------KSTQTLFVRLGAYNIN-------H----- 94

  Fly   189 ADCAPPYQDIAIEELLPHPLYNRTDRTQINDIALVRLASPAKLNDFVQPICLP-----NKQLRAD 248
                 |...|.:.|.:.||.|:.:  |..||||||:|......|..:||||:.     .||:|
  Fly    95 -----PTDQIRVIETIAHPQYSNS--TYANDIALVKLERSVIFNLNIQPICIHLDATLGKQIR-- 150

  Fly   249 ELEDLVTEVAGW----QASSSQRMRKGYVTISSIEECQRKYASQQLRIQASKLCGLTNSQE-CYG 308
                 .....||    .|..|..:::.:|..::...|   :....:.....::|..|:..: |.|
  Fly   151 -----YYNAFGWGRTRNAEQSDILQRIFVNRTNPMIC---HLYLGMSPDPKQICATTDQGDTCAG 207

  Fly   309 NAGGPL---MLFKNDGY-LLGGLVSFGPVPCPNPDWPDVYTRVASYIDWIHDSLKA 360
            ::||||   :.::...: ...|:.|:|...|   :...:||.|:.|..||.:.:::
  Fly   208 DSGGPLISKITYQGKNFDTQFGITSYGTREC---NGVGLYTDVSQYSGWIANIVRS 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3505	NP_650380.2	CLIP	30..82	CDD:288855
		Tryp_SPc	111..356	CDD:238113	65/245 (27%)
		Tryp_SPc	111..354	CDD:214473	63/243 (26%)
CG43110	NP_001246396.1	Tryp_SPc	35..254	CDD:214473	63/243 (26%)
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	65/246 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463487
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940