Protein Alignment CG3505 and KLK11

DIOPT Version :10

• Sequence 1: NP_650380.2
• Gene: CG3505 / 41777
• FlyBaseID: FBgn0038250
• Length: 360
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 87/339 - (25%)
• Similarity: 144/339 - (42%)
• Gaps: 86/339 - (25%)

  Fly    61 SDRNLLRDNQCGVRGNDVQ--------VCCPSTAGLGALTHPLLPSDCGKVRWQRSNDTDTRIRE 117
            |.|.|....:.|.|.:.:|        :...:|..:|..|..:...:|             :...
Human    13 SGRGLTAAKEPGARSSPLQAMRILQLILLALATGLVGGETRIIKGFEC-------------KPHS 64

  Fly   118 FPW-LALIEYTRGNQEKIHACGGVLISDRYVLTAAHCV------------------AQAATSNLQ 163
            .|| .||.|.||      ..||..||:.|::||||||:                  :....|:|.
Human    65 QPWQAALFEKTR------LLCGATLIAPRWLLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLS 123

  Fly   164 ITAVRLGEWDTSTNPDCQYHEDSKVADCAPPYQDIAIEELLPHPLYNRT--DRTQINDIALVRLA 226
            ...|.||:.:......|   |.::.|           .|..|||.:|.:  ::...|||.||::|
Human   124 RYIVHLGQHNLQKEEGC---EQTRTA-----------TESFPHPGFNNSLPNKDHRNDIMLVKMA 174

  Fly   227 SPAKLNDFVQPICLPNKQLRADELEDLVTE--VAGWQASSSQRMRKGY------VTISSIEECQR 283
            ||..:...|:|:.|.::.:.|.      |.  ::||.::||.::|..:      :||...::|:.
Human   175 SPVSITWAVRPLTLSSRCVTAG------TSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCEN 233

  Fly   284 KYASQQLRIQASKLCGLT---NSQECYGNAGGPLMLFKNDGYLLGGLVSFGPVPCPNPDWPDVYT 345
            .|..   .|..:.:|...   ....|.|::||||:..::    |.|::|:|..||.....|.|||
Human   234 AYPG---NITDTMVCASVQEGGKDSCQGDSGGPLVCNQS----LQGIISWGQDPCAITRKPGVYT 291

  Fly   346 RVASYIDWIHDSLK 359
            :|..|:|||.:::|
Human   292 KVCKYVDWIQETMK 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3505	NP_650380.2	CLIP	32..82	CDD:463440	6/28 (21%)
		Tryp_SPc	111..356	CDD:238113	76/276 (28%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	75/292 (26%)