DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3505 and LOC100004411

DIOPT Version :9

Sequence 1:	NP_650380.2	Gene:	CG3505 / 41777	FlyBaseID:	FBgn0038250	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_001343728.4	Gene:	LOC100004411 / 100004411	-ID:	-	Length:	494	Species:	Danio rerio

Alignment Length:	269	Identity:	81/269 - (30%)
Similarity:	134/269 - (49%)	Gaps:	55/269 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 DTRI------RE--FPWLALIEYTRGNQEKIHACGGVLISDRYVLTAAHCVAQAATSNLQITAVR 168
            ||||      |:  .||..|:.    .:::...|||.||:.|:|:|||||:.|....      :.
Zfish   246 DTRIVGGQLQRQGGSPWQVLLR----REDEYGFCGGSLINQRWVITAAHCLQQTPHH------IT 300

  Fly   169 LGEWDTSTNPDCQYHEDSKVADCAPPYQDIAIEELLPHPLYNRTDRTQINDIALVRLASPAKLND 233
            :|::| ...||    :|.         |.|.:|:::|||.|:  :.|..:||||:.|:|...|..
Zfish   301 IGDYD-KMRPD----KDE---------QKITVEKIIPHPHYH--EYTFDSDIALLYLSSAVTLGP 349

  Fly   234 FVQPICLPNKQLRADEL-----EDLVTEVAGWQAS-----SSQRMRKGYVTISSIEECQRKYASQ 288
            |..|.|||:..| |:.|     :.|   |:||.::     ||:.:||  |.:..:|:.....:::
Zfish   350 FASPACLPDANL-AERLMKPGEQGL---VSGWGSTHYLQRSSRFLRK--VQLPVVEQKSCINSTE 408

  Fly   289 QLRIQASKLCG---LTNSQECYGNAGGPLMLFKNDGYLLGGLVSFGPVPCPNPDWPDVYTRVASY 350
            |: |..:..|.   :.....|.|::|||.::.....:.|.|:||:|. .|.:.....||||:.:|
Zfish   409 QI-ITDNMFCAGFLMEEMDACTGDSGGPFIVNYRGTWFLTGVVSWGE-RCASQGKYGVYTRLGNY 471

  Fly   351 IDWIHDSLK 359
            :.||.:.:|
Zfish   472 LSWIQEEMK 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3505	NP_650380.2	CLIP	30..82	CDD:288855
		Tryp_SPc	111..356	CDD:238113	80/264 (30%)
		Tryp_SPc	111..354	CDD:214473	78/262 (30%)
LOC100004411	XP_001343728.4	GLA	22..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	128..164	CDD:291342
		Tryp_SPc	248..475	CDD:214473	76/260 (29%)
		Tryp_SPc	249..477	CDD:238113	77/261 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920