| Sequence 1: | NP_650378.1 | Gene: | CG7886 / 41775 | FlyBaseID: | FBgn0038248 | Length: | 818 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001269072.1 | Gene: | NLRX1 / 79671 | HGNCID: | 29890 | Length: | 975 | Species: | Homo sapiens |
| Alignment Length: | 466 | Identity: | 93/466 - (19%) |
|---|---|---|---|
| Similarity: | 161/466 - (34%) | Gaps: | 136/466 - (29%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 88 EALHYDLVLQQ-----LVVRLRRTYPQTNIDPIDTEKRARLFRQRPVI-------YTRFIFNSL- 139
Fly 140 -----VQAIANCVSSNKNLSVLKLEGLPLQDGYIETIAKALADN--------------ECLESVS 185
Fly 186 FRKSNI-GDKGCEVVCNTAKYL-----NRIEVFDLSECGLTSKGAEHVADM-LKMQKITRFTEGW 243
Fly 244 EKSLRYRSVDVNTIGGLRTVLLAD----------NPEIGDVGIRWITEVLKEDAWIKKIDMEGCG 298
Fly 299 LTDIGANLILDCLELNTAITEFNVRNNEGISKFLQRSIHDRLGCLPEEKQEPEYDLSCVNGLQSL 363
Fly 364 PKNKKVTVSQLLSHTKALEEQLSFERTLRKKAEKLNEKLSHQLMRPDSNHMVQEKAMEGGSQTNI 428
Fly 429 S-REYVARND----VMPEVIKNSQSYRQSHFNRLVNSAATSPEVTPRSEIVTLRKEQQLQRQQPP 488
Fly 489 PMEVKHLSLEQ 499 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG7886 | NP_650378.1 | LRR_RI | <142..320 | CDD:238064 | 41/208 (20%) |
| leucine-rich repeat | 153..180 | CDD:275381 | 6/40 (15%) | ||
| leucine-rich repeat | 181..208 | CDD:275381 | 7/32 (22%) | ||
| leucine-rich repeat | 209..246 | CDD:275381 | 6/37 (16%) | ||
| leucine-rich repeat | 260..285 | CDD:275381 | 9/34 (26%) | ||
| NLRX1 | NP_001269072.1 | Required for interaction with MAVS. /evidence=ECO:0000269|PubMed:18200010 | 75..556 | ||
| P-loop_NTPase | 161..320 | CDD:304359 | |||
| Required for the repression of MAVS-induced interferon signaling | 556..974 | 93/466 (20%) | |||
| LRR_RI | <698..885 | CDD:238064 | 42/241 (17%) | ||
| leucine-rich repeat | 698..726 | CDD:275380 | 5/29 (17%) | ||
| leucine-rich repeat | 745..772 | CDD:275380 | 5/35 (14%) | ||
| leucine-rich repeat | 773..808 | CDD:275380 | 7/34 (21%) | ||
| leucine-rich repeat | 809..836 | CDD:275380 | 7/26 (27%) | ||
| leucine-rich repeat | 865..886 | CDD:275380 | 5/22 (23%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG4308 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||