Protein Alignment CG7886 and Lrrc74a

DIOPT Version :9

• Sequence 1: NP_650378.1
• Gene: CG7886 / 41775
• FlyBaseID: FBgn0038248
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: NP_001182696.1
• Gene: Lrrc74a / 627607
• MGIID: 3646959
• Length: 487
• Species: Mus musculus
• Alignment Length: 504
• Identity: 104/504 - (20%)
• Similarity: 190/504 - (37%)
• Gaps: 147/504 - (29%)

  Fly   109 QTNIDPIDTEK------------RARLFRQRPVIYTRFIFNSLVQAIANCVSSN----------- 150
            :|:::..||||            ..:|....|..|  ||.|    ...:||:.|
Mouse    51 ETDLEIEDTEKFFNIGQKELYLEACKLVGVVPASY--FIRN----MEESCVNLNHHGLGPMGTKA 109

  Fly   151 ------KNLSVLKLEGLPLQDGYIE-----TIAKALADNECLESVSFRKSNIGDKGCEVVCNTAK 204
                  .|.:|||||   |.|..|:     ::.:.|.:|..|:.::...:|:|.:|..::.|..:
Mouse   110 IAITLVSNTTVLKLE---LGDNCIQEEGIMSLMEMLHENYYLQELNVSDNNLGLEGARIISNFLQ 171

  Fly   205 YLNRIEVFDLSECGLTSKGAEHVADMLKMQKITRFTEGWEKSLRYRSVDV-----NTIGGLRT-V 263
            . |...::.|...|.:.|  |..|.:|        .:....:.|.||:::     :.|||... .
Mouse   172 E-NNSSLWKLKLSGNSFK--EECAALL--------CQALSSNYRIRSLNLSHNEFSDIGGEHLGQ 225

  Fly   264 LLADNPEIGDVGIRW----------ITEVLKEDAWIKKIDMEGCGLTDIGANLILDCLELNTAIT 318
            :||.|..:..:.:.|          :...|:.:..:||:|:...|..:.||..:.|.|.||:.:.
Mouse   226 MLALNVGLQSLNLSWNHFNIRGAVALCNGLRSNVTLKKLDVSMNGFGNEGALALGDALRLNSCLV 290

  Fly   319 EFNV-RN---NEGISKFLQRSIHDRLGCLPEEKQEPEYDLSCVNGLQSLPKNKKVTVSQLLSHTK 379
            ..:| ||   |||.||..:                         ||::   |:.:.|.:|..:..
Mouse   291 YVDVSRNGITNEGASKISK-------------------------GLEN---NECLQVLKLFLNPL 327

  Fly   380 ALEEQLSFERTLRKKAEKLNEKLSHQLMRPDSNHMVQE---KAMEG-------------GSQTNI 428
            :||...|....:::..:...|.:.      .||.:|.|   |.::|             |.|...
Mouse   328 SLEGAYSLIMAIKRNPKSRMEDID------ISNVLVSEQFVKVLDGVCAIHPQLDVVYKGLQGLS 386

  Fly   429 SREYVARNDVMPEVIKNSQSYRQS------HFNRLVNSAA--TSPEVTPRSEIVTLRKEQQLQRQ 485
            :::.::.......:|   |||.:.      .|.|.:|...  |.|....|..::
Mouse   387 TKKSISLGTNPMRLI---QSYTEQKKISVVEFFRSLNPTGLMTMPVGDFRKAMI----------- 437

  Fly   486 QPPPMEVKHLSLEQQIRNLRDVQKKVDL-DVEEEEEEEEEEQQAEESQS 533
            |...:.:....:.:.|:.|.:.:..|:. .:|:|:..:..|.:.||.||
Mouse   438 QQSNILINRYQVRELIKKLDEKKGMVNFSSLEKEDLSKTVEPKPEELQS 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7886	NP_650378.1	LRR_RI	<142..320	CDD:238064	47/215 (22%)
		leucine-rich repeat	153..180	CDD:275381	10/31 (32%)
		leucine-rich repeat	181..208	CDD:275381	5/26 (19%)
		leucine-rich repeat	209..246	CDD:275381	6/36 (17%)
		leucine-rich repeat	260..285	CDD:275381	5/35 (14%)
Lrrc74a	NP_001182696.1	LRR_RI	73..333	CDD:393385	68/307 (22%)
		leucine-rich repeat	148..176	CDD:275380	6/28 (21%)
		leucine-rich repeat	177..204	CDD:275380	6/36 (17%)
		leucine-rich repeat	205..232	CDD:275380	8/26 (31%)
		leucine-rich repeat	233..257	CDD:275380	2/23 (9%)
		leucine-rich repeat	261..284	CDD:275380	7/22 (32%)
		leucine-rich repeat	285..313	CDD:275380	12/52 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900