| Sequence 1: | NP_650378.1 | Gene: | CG7886 / 41775 | FlyBaseID: | FBgn0038248 | Length: | 818 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_038460.4 | Gene: | TONSL / 4796 | HGNCID: | 7801 | Length: | 1378 | Species: | Homo sapiens |
| Alignment Length: | 803 | Identity: | 144/803 - (17%) |
|---|---|---|---|
| Similarity: | 250/803 - (31%) | Gaps: | 280/803 - (34%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 118 EKRARLFRQRPVIYTRFIFNSLVQAIANCVSSNKNLSVLKLEGLPLQDGYIETIAKALADNECLE 182
Fly 183 SVSFRKSNIGDKGCEVVCNTAKYLNRIEVFDLSECGLTSKGAEHVADML-KMQKITRFTEGWEKS 246
Fly 247 LRYRSVDVNTIGGLRTVL---LADNPEIGDV-----GIRWITEVLK-------EDA--WIK-KID 293
Fly 294 MEGCGLTDIGANLILDCLELNTAITEFNVRNNEGISKFLQRSIHDRLGCL-----PEEKQEPEYD 353
Fly 354 LSCVNGLQSLPKNKKVTVSQLLSHTKALE-----------------EQLSFERTL-----RKKAE 396
Fly 397 KLN------EKLSHQLMRPDSNHMVQEKAMEGGSQTNISREYV-------ARNDVMPEVIKNSQS 448
Fly 449 YRQSHFNRLVNSAATSP------EVTP------------------RSEIVTLRKEQQLQRQQPPP 489
Fly 490 MEVKHLSLEQQIRNLRDVQKKVDLDVEEEEEEEEEEQQAEESQSESEPQNEEQQHYEQQM----- 549
Fly 550 -------------------QVQRKHLQVRKVRSEIKYVENNPKEAA------KKNRESKSDHEFA 589
Fly 590 NERDFKLNPSVQFETDIGDNVMVNPGHRYEGGGGDTAYVYNY------EHEQQQQPVKRGYEHGY 648
Fly 649 VVGVGDGSHRRQRQSQLVEALVQKRVPGASDGH----VAQFVSNLERQANAGK--------TGKK 701
Fly 702 RLKPRPEDDLQVP---VGDMHMESSYMSRSEELSSTDVTLENSDYETEATDSTLLSSSKYSSMHV 763
Fly 764 FVRRKQSESMSLTEEAGDGDAGG 786 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG7886 | NP_650378.1 | LRR_RI | <142..320 | CDD:238064 | 35/196 (18%) |
| leucine-rich repeat | 153..180 | CDD:275381 | 3/26 (12%) | ||
| leucine-rich repeat | 181..208 | CDD:275381 | 6/26 (23%) | ||
| leucine-rich repeat | 209..246 | CDD:275381 | 5/37 (14%) | ||
| leucine-rich repeat | 260..285 | CDD:275381 | 8/39 (21%) | ||
| TONSL | NP_038460.4 | TPR_12 | 23..99 | CDD:290160 | |
| TPR 1 | 27..60 | ||||
| TPR repeat | 27..55 | CDD:276809 | |||
| TPR repeat | 66..96 | CDD:276809 | |||
| TPR 2 | 67..100 | ||||
| TPR 3 | 107..147 | ||||
| TPR repeat | 107..131 | CDD:276809 | |||
| TPR 4 | 162..195 | ||||
| TPR repeat | 163..190 | CDD:276809 | |||
| TPR | 187..>418 | CDD:223533 | 42/215 (20%) | ||
| TPR repeat | 195..231 | CDD:276809 | |||
| TPR 5 | 202..235 | ||||
| TPR 6 | 242..275 | 3/8 (38%) | |||
| TPR repeat | 242..270 | CDD:276809 | 1/3 (33%) | ||
| TPR repeat | 276..300 | CDD:276809 | 8/53 (15%) | ||
| TPR 7 | 311..344 | 10/57 (18%) | |||
| TPR repeat | 316..339 | CDD:276809 | 5/22 (23%) | ||
| TPR repeat | 351..381 | CDD:276809 | 8/31 (26%) | ||
| TPR 8 | 352..385 | 7/34 (21%) | |||
| TPR repeat | 390..419 | CDD:276809 | 6/31 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 475..524 | 9/48 (19%) | |||
| ANK | 523..635 | CDD:238125 | 23/127 (18%) | ||
| ANK repeat | 528..559 | CDD:293786 | 6/32 (19%) | ||
| ANK 1 | 528..557 | 6/30 (20%) | |||
| Ank_2 | 533..627 | CDD:289560 | 17/104 (16%) | ||
| ANK repeat | 561..592 | CDD:293786 | 5/39 (13%) | ||
| ANK 2 | 561..590 | 5/37 (14%) | |||
| ANK repeat | 594..627 | CDD:293786 | 5/32 (16%) | ||
| ANK 3 | 597..626 | 4/28 (14%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 667..789 | 14/146 (10%) | |||
| PRR18 | 707..>919 | CDD:292299 | 45/262 (17%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 842..933 | 21/93 (23%) | |||
| LRR_RI | 1045..1306 | CDD:238064 | |||
| LRR 1 | 1069..1093 | ||||
| LRR_8 | 1072..1141 | CDD:290566 | |||
| leucine-rich repeat | 1072..1099 | CDD:275380 | |||
| LRR 2 | 1097..1122 | ||||
| leucine-rich repeat | 1100..1130 | CDD:275380 | |||
| LRR 3 | 1128..1151 | ||||
| leucine-rich repeat | 1131..1158 | CDD:275380 | |||
| leucine-rich repeat | 1159..1190 | CDD:275380 | |||
| LRR 4 | 1188..1212 | ||||
| leucine-rich repeat | 1191..1215 | CDD:275380 | |||
| leucine-rich repeat | 1216..1249 | CDD:275380 | |||
| LRR 5 | 1247..1270 | ||||
| leucine-rich repeat | 1250..1277 | CDD:275380 | |||
| LRR 6 | 1275..1300 | ||||
| leucine-rich repeat | 1278..1300 | CDD:275380 | |||
| leucine-rich repeat | 1308..1333 | CDD:275380 | |||
| LRR 7 | 1331..1354 | ||||
| leucine-rich repeat | 1334..1355 | CDD:275380 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG4308 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||