DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG7886 and Nlrp9a

DIOPT Version :9

Sequence 1:NP_650378.1 Gene:CG7886 / 41775 FlyBaseID:FBgn0038248 Length:818 Species:Drosophila melanogaster
Sequence 2:NP_001041684.1 Gene:Nlrp9a / 233001 MGIID:2675292 Length:1004 Species:Mus musculus


Alignment Length:420 Identity:85/420 - (20%)
Similarity:150/420 - (35%) Gaps:126/420 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    70 FLEL----CGD--------KLAVSDWQLL-----------TEALHYDLVLQQLVVRLRRTYPQTN 111
            |||:    .||        ||....|..|           .::.|::   ::.:..|....|.|:
Mouse   599 FLEIHDPEYGDLELFKLDQKLLAKHWTTLCTFLCNLHVLDLDSCHFN---EKAIEVLCNCLPLTS 660

  Fly   112 IDPIDTEKRARLFRQRPVIYTRF----IFNSLVQAIANCVSSNKNLSVLKLEGLPLQDGYIETIA 172
            :.|:...|..||...   ..|.|    :|.:.:..        .:|..:.|.|..|.:..:|.:.
Mouse   661 LVPLTGFKLHRLLCS---FTTNFGDGLLFCTFLHL--------PHLKYMNLYGTNLSNDAVERLC 714

  Fly   173 KALADNEC-LESVSFRKSNIGDKGCEVVCNTAKYLN-RIEVFDLSECGLTSKGAEHVADMLK--- 232
            .||..:.| :|.:...|.:|..:.|.::  .|..:| .::...|.|..|.:||...:.:|||   
Mouse   715 SALKFSTCGVEELLLGKCDISSEACGII--AASLINSEVKHLSLVENPLKNKGVMSLCEMLKDPS 777

  Fly   233 --MQKITRFTEGWEKSLRYRSVDVNTIGGLRTVLLADNP----EIG-----DVGIRWITEVLKE- 285
              ::.:         .|.|..:.....|.|...||::..    ::|     |.|:..:.|.||: 
Mouse   778 CVLESL---------MLSYCCLTFIACGHLYEALLSNEHLSLLDLGSNFLEDTGVNLLCEALKDP 833

  Fly   286 DAWIKKIDMEGCGLTDIGANLILDCLELNTAITEFNVRNNE----GISKFLQRSIHDRLGCLPEE 346
            :..:|::.:.||.||......|...|..||.:....:.||.    |:.:..:...|         
Mouse   834 NCTLKELWLPGCYLTSECCEEISAVLTCNTNLKTLKLGNNNIQDTGVKRLCEALCH--------- 889

  Fly   347 KQEPEYDLSCV-------------------------------------NGLQSLPK--NKKVTVS 372
               |..::.|:                                     :||:.|.|  |.|....
Mouse   890 ---PNCEMQCLGLDMCDFTSDCCEDLALVLTTCNTLKSLNLDWNAFDHSGLEMLCKALNHKACNL 951

  Fly   373 QLLSHTKALEEQLSFERTLRKKAEKLNEKL 402
            ::|...|:|..:.|  :||.:..||.|:.|
Mouse   952 EVLGLDKSLFSEES--QTLLQAVEKKNKNL 979

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7886NP_650378.1 LRR_RI <142..320 CDD:238064 43/194 (22%)
leucine-rich repeat 153..180 CDD:275381 7/26 (27%)
leucine-rich repeat 181..208 CDD:275381 6/27 (22%)
leucine-rich repeat 209..246 CDD:275381 8/41 (20%)
leucine-rich repeat 260..285 CDD:275381 8/33 (24%)
Nlrp9aNP_001041684.1 Pyrin_NALPs 9..91 CDD:260032
NACHT 144..303 CDD:283404
LRR_RI 693..957 CDD:238064 56/286 (20%)
leucine-rich repeat 695..716 CDD:275380 5/20 (25%)
leucine-rich repeat 717..748 CDD:275380 7/32 (22%)
leucine-rich repeat 751..779 CDD:275380 8/27 (30%)
leucine-rich repeat 780..807 CDD:275380 6/35 (17%)
leucine-rich repeat 808..835 CDD:275380 6/26 (23%)
leucine-rich repeat 837..864 CDD:275380 8/26 (31%)
leucine-rich repeat 894..921 CDD:275380 1/26 (4%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4308
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.