Protein Alignment CG7886 and LRRC71

DIOPT Version :9

• Sequence 1: NP_650378.1
• Gene: CG7886 / 41775
• FlyBaseID: FBgn0038248
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: XP_005244983.1
• Gene: LRRC71 / 149499
• HGNCID: 26556
• Length: 560
• Species: Homo sapiens
• Alignment Length: 512
• Identity: 101/512 - (19%)
• Similarity: 187/512 - (36%)
• Gaps: 153/512 - (29%)

  Fly    15 GEVA--RKPNTVVVSVPPLVKKSSKSRS-------FHFRYLELCRAKNLTPVPEIRSKSNATTTF 70
            ||.|  .||.||   :||:.::..||..       ....:.|||.....|..|::.::......|
Human    30 GERAAKEKPATV---LPPVGEEEPKSPEEYQCSGVLETDFAELCTRWGYTDFPKVVNRPRPHPPF 91

  Fly    71 LELC--GDKLAVSDWQLLTE-ALHYDLVLQQLVVRLRRTYPQTNIDPIDTEKRARLFRQRPVIYT 132
            :...  .:|..:.|.:|... :|:   .|:...|..|.|. |..::..|::....::.:...:..
Human    92 VPSASLSEKATLDDPRLSGSCSLN---SLESKYVFFRPTI-QVELEQEDSKSVKEIYIRGWKVEE 152

  Fly   133 RFI---------------------------FNSLVQAIANCVSSNKNLSVLKLEGLPLQDGYIET 170
            |.:                           ..:.::.:..|.|:.:.:|   |||.||.:   ::
Human   153 RILGVFSKCLPPLTQLQAINLWKVGLTDKTLTTFIELLPLCSSTLRKVS---LEGNPLPE---QS 211

  Fly   171 IAKALADNECLESVSFRKSNIGDKGCEVV---CNTAKYLNRIEV-FDLSECGLTSKGAEHVADML 231
            ..|.:|.:..:..:|.|.:||.|:|.:::   .:|....||..| .:|....:..:||.::||.|
Human   212 YHKLMALDSTIAHLSLRNNNIDDRGAQLLGQALSTLHSCNRTLVSLNLGFNHIGDEGAGYIADGL 276

  Fly   232 KMQKITRFTEGWEKSLRYRSVDVNTI---GGLRTVLLADNPEIGDVGIRWITEVLKEDAWI---- 289
            ::          .:||.:.|:..|.|   |.|:...:....|:..      |||::....:
Human   277 RL----------NRSLLWLSLAHNRIQDKGALKLAEVLRAFELTH------TEVVERRRLLLEKG 325

  Fly   290 ---------------KKIDMEGCGLTDIGANLILDCLELNTAITEFNVRNNEGISKFLQRS---- 335
                           .|.|.|...:..|..:.::|    .|..|: .::..:|:.|..::|
Human   326 TQERSRSPSSSRHGDSKTDREKSQMVGISNSALVD----KTDKTQ-TMKTPKGLGKKKEKSWELA 385

  Fly   336 -IHDRLGCLPEEKQEPEYDLSCVNGLQSLPKNK--------KVTV-SQLLSHTKALE-------- 382
             ..::||    ..|.|         .|..||.:        |||: .|..|..|.::
Human   386 KKEEKLG----SGQSP---------TQGTPKKEDATKAGKGKVTIPEQKPSRAKGIKIGSREKRS 437

  Fly   383 -----EQLSFERTLRKKAEKLNEKLSH---QLMRPDSN---HM------VQEKAMEG 422
                 |||..|.|  :....|.|.:.|   ::..|.:.   |:      :.|..:||
Human   438 ILLESEQLVVEAT--EVVNPLLEPVEHRDGKVFMPGNKVLLHLNLIRNRITEVGLEG 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7886	NP_650378.1	LRR_RI	<142..320	CDD:238064	44/203 (22%)
		leucine-rich repeat	153..180	CDD:275381	8/26 (31%)
		leucine-rich repeat	181..208	CDD:275381	7/29 (24%)
		leucine-rich repeat	209..246	CDD:275381	7/37 (19%)
		leucine-rich repeat	260..285	CDD:275381	5/24 (21%)
LRRC71	XP_005244983.1	LRR_RI	<161..308	CDD:238064	33/162 (20%)
		leucine-rich repeat	168..196	CDD:275380	1/27 (4%)
		leucine-rich repeat	197..217	CDD:275380	7/25 (28%)
		leucine-rich repeat	218..243	CDD:275380	6/24 (25%)
		leucine-rich repeat	254..281	CDD:275380	7/36 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900