Protein Alignment CG7886 and LRRC74A

DIOPT Version :9

• Sequence 1: NP_650378.1
• Gene: CG7886 / 41775
• FlyBaseID: FBgn0038248
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: XP_011534781.1
• Gene: LRRC74A / 145497
• HGNCID: 23346
• Length: 529
• Species: Homo sapiens
• Alignment Length: 421
• Identity: 82/421 - (19%)
• Similarity: 155/421 - (36%)
• Gaps: 120/421 - (28%)

  Fly   141 QAIANCVSSNKNLSVLKLEGLPLQDGYIETIAKALADNECLESVSFRKSNIGDKGCEVV------ 199
            :|||..:.||..::.|:||...:.:..:.::.:.|.:|..|:.::...:::|.:|..::
Human   139 KAIAIALVSNMAVTKLELEDNCIMEEGVLSLVEMLQENYYLQEMNISNNHLGLEGARIISDFFER 203

  Fly   200 -----------------------CNTAKYLNRIEVFDLSECGLTSKGAEHVADMLKMQ-KITRFT 240
                                   |.......:|:..|||....:..|.||:..||.:. .:|...
Human   204 NSSSIWSLELSGNDFKEDSAALLCQALSTNYQIKKLDLSHNQFSDVGGEHLGQMLAINVGLTSLD 268

  Fly   241 EGWEKSLRYRSVDVNTIGGLRTVLLADNPEIGDVGIRWITEVLKEDAWIKKIDMEGCGLTDIGAN 305
            ..|.        :.:|.|   .|.|.:.              |:.:..:.|:|:...|..:..|.
Human   269 LSWN--------NFHTRG---AVALCNG--------------LRGNVTLTKLDLSMNGFGNEVAL 308

  Fly   306 LILDCLELNTAITEFNVR----NNEGISKFLQRSIHDRLGCLPEEKQEPEYDLSCVNGLQSLPKN 366
            .:.:.|.||..:...::.    .|||.||..:                         ||:|   |
Human   309 ALGEVLRLNRCLVYLDIGGNDIGNEGASKISK-------------------------GLES---N 345

  Fly   367 KKVTVSQL----LSHTKALEEQLSFERTLRKKAEKL---NEKLSHQLMRP-DSNHMVQE------ 417
            :.:.|.:|    ::...|:...|:.:|..:.:.|:|   |..:|.|.|:. |..:.|..
Human   346 ESLRVLKLFLNPINMDGAILLILAIKRNPKSRMEELDISNVLVSEQFMKTLDGVYAVHPQLDVVF 410

  Fly   418 KAMEGGSQTNISREYVARNDVMPEVIKNSQSYRQSHFNRLVN-SAATSPEVTPRSEIVTLRKEQQ 481
            ||::|.|.....  ::..|.     :|..|||...|...:|: ..:.:|..|.:..:...:|...
Human   411 KAVQGLSPKKTI--FLLTNP-----MKLIQSYADQHKITIVDFFKSLNPTGTMKMSVDEFQKVMI 468

  Fly   482 LQRQQPPPMEVKHLSLEQQIRNLRDVQKKVD 512
            .|.:.|         |.|.  .:|:|.||:|
Human   469 EQNKVP---------LNQY--QVREVIKKLD 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7886	NP_650378.1	LRR_RI	<142..320	CDD:238064	37/207 (18%)
		leucine-rich repeat	153..180	CDD:275381	5/26 (19%)
		leucine-rich repeat	181..208	CDD:275381	4/55 (7%)
		leucine-rich repeat	209..246	CDD:275381	11/37 (30%)
		leucine-rich repeat	260..285	CDD:275381	3/24 (13%)
LRRC74A	XP_011534781.1	LRR_RI	128..384	CDD:330982	53/297 (18%)
		leucine-rich repeat	152..174	CDD:275380	3/21 (14%)
		leucine-rich repeat	179..207	CDD:275380	3/27 (11%)
		leucine-rich repeat	208..235	CDD:275380	1/26 (4%)
		leucine-rich repeat	236..259	CDD:275380	8/22 (36%)
		leucine-rich repeat	264..291	CDD:275380	7/51 (14%)
		leucine-rich repeat	292..319	CDD:275380	7/26 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900